Cadenat H, Combelles R, Fabert G, Clouet M
Rev Stomatol Chir Maxillofac. 1977;78(5):341-6.
The authors describe the case of mesiodens in two non-identical twins and in their grandfather. They recall that, although no investigation confirmed the hereditary nature of the mesiodens, it is quite undeniable in view of the frequency of familial cases. They think there is a recessive gene on an autosome and a gene on the inhibiting chromosome X. They discount the theory of mutation.
作者描述了两例非同卵双胞胎及其祖父患正中牙的病例。他们提到,尽管没有调查证实正中牙的遗传性,但鉴于家族病例的出现频率,其遗传性是不可否认的。他们认为常染色体上存在一个隐性基因,以及抑制性X染色体上存在一个基因。他们对突变理论不予考虑。