Zhao Jiaqi, Zhang Jianquan, Xu Qi, Sheng Jianguo, Diao Zongping, Liu Shiyuan
Department of Ultrasound, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China.
Department of Computer Science, Institute of Information Engineering, Shanghai Maritime University, Shanghai, 201306, China.
J Med Ultrason (2001). 2016 Jul;43(3):337-45. doi: 10.1007/s10396-016-0708-y. Epub 2016 Apr 15.
This study aimed to use the multiscale blob feature (MBF) method to quantitatively evaluate porcine striated muscle injuries.
A porcine striated muscle injury model was induced by microwave ablation and anhydrous acetic acid injection, respectively. Then, both 2D sonographic and histological features of the lesions were recorded and compared. Later, MBF was used to quantitatively evaluate the porcine striated muscle injuries by extracting the texture features from the 2D ultrasonogram via measuring eight textural parameters (Mean, SDev, NOB, [Formula: see text], [Formula: see text], HOD, DOD, and POD).
Microwave ablation produced oval or round-like lesions, which had a pale gray color, with an echo attenuation detected at lesion center due to carbonization; anhydrous acetic acid injection produced long, stripped lesions, which had a slate-gray color, with a gas-like intense echo at lesion center. There were significant differences in Mean, [Formula: see text] and POD between the muscle samples treated by microwave ablation and the control samples, as well as significant differences in NOB, [Formula: see text] and POD between the muscle samples treated by anhydrous acetic acid injection and the control. There were significant differences in Mean, [Formula: see text], NOB, and [Formula: see text] between the muscle samples treated by microwave ablation and those treated by anhydrous acetic acid injection.
Quantitative evaluation of striated muscle injuries using the MBF method was able to differentiate the muscle injuries caused by microwave ablation and anhydrous acetic acid injection, suggesting that this method may be a potential and reliable tool for quantitative evaluation of muscle injuries.
本研究旨在使用多尺度斑点特征（MBF）方法对猪横纹肌损伤进行定量评估。
分别通过微波消融和注射无水乙酸诱导建立猪横纹肌损伤模型。然后，记录并比较病变的二维超声特征和组织学特征。随后，通过测量八个纹理参数（均值、标准差、斑点数、[公式：见原文]、[公式：见原文]、高灰度差、低灰度差和峰度）从二维超声图像中提取纹理特征，使用MBF方法对猪横纹肌损伤进行定量评估。
微波消融产生椭圆形或圆形病变，颜色呈浅灰色，由于碳化在病变中心检测到回声衰减；注射无水乙酸产生长条状病变，颜色呈石板灰色，在病变中心有类似气体的强回声。微波消融处理的肌肉样本与对照样本之间在均值、[公式：见原文]和峰度上存在显著差异，注射无水乙酸处理的肌肉样本与对照之间在斑点数、[公式：见原文]和峰度上存在显著差异。微波消融处理的肌肉样本与注射无水乙酸处理的肌肉样本之间在均值、[公式：见原文]、斑点数和[公式：见原文]上存在显著差异。
使用MBF方法对横纹肌损伤进行定量评估能够区分微波消融和注射无水乙酸所导致的肌肉损伤，表明该方法可能是一种用于肌肉损伤定量评估的潜在且可靠的工具。
