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婴儿期主动脉缩窄修复术:10年临床经验

Repair of aortic coarctation in infancy: A 10-year clinical experience.

作者信息

Bigdelian Hamid, Sedighi Mohsen

机构信息

Department of Cardiovascular Surgery, Chamran Heart Center, Isfahan University of Medical Science, Isfahan, Iran.

Department of Cardiovascular Surgery, Chamran Heart Center, Isfahan University of Medical Science, Isfahan, Iran

出版信息

Asian Cardiovasc Thorac Ann. 2016 Jun;24(5):417-21. doi: 10.1177/0218492316643841. Epub 2016 Apr 15.

Abstract

BACKGROUND

Coarctation of the aorta is a congenital narrowing of the upper descending aorta. The approximate incidence is 4% in live-born children with congenital heart disease. This study aimed to describe the surgical outcome and survival of patients undergoing congenital aortic coarctation repair via subclavian flap aortoplasty (group 1) or resection with end-to-end anastomosis (group 2).

METHODS

We retrospectively reviewed the clinical outcomes of 105 infants who underwent repair of aortic coarctation between 2000 and December 2012. Fifty patients (group 1) underwent subclavian flap aortoplasty and 55 (group 2) underwent resection with end-to-end anastomosis. Procedure details and early results were collected by retrospective review of hospital and clinic data.

RESULTS

The mean age of patients in group 1 was 6.73 ± 1.1 vs. 6.76 ± 1.2 months in group 2, and the mean weight was 6.01 ± 1.3 vs. 5.9 ± 1.0 kg, respectively. There were no significant differences among the intra- and postoperative variables in the 2 groups. Six patients in group 1 had a peak systolic gradient >20 mm Hg. The recurrence rate in group 1 was 12% vs. 1.8% in group 2 (p < 0.05). Overall mortality was 2.8%. Survival in group 1 was 96% vs. 98.2% in group 2.

CONCLUSION

Repair of aortic coarctation in infancy by resection with end-to-end anastomosis can be performed with a low mortality rate and a low incidence of recoarctation, and it provides the optimal prognosis for coarctation in infancy.

摘要

背景

主动脉缩窄是降主动脉上段的先天性狭窄。在患有先天性心脏病的活产婴儿中,其发病率约为4%。本研究旨在描述通过锁骨下皮瓣主动脉成形术(第1组)或端到端吻合切除术(第2组)进行先天性主动脉缩窄修复的患者的手术结果和生存率。

方法

我们回顾性分析了2000年至2012年12月期间接受主动脉缩窄修复的105例婴儿的临床结果。50例患者(第1组)接受锁骨下皮瓣主动脉成形术,55例(第2组)接受端到端吻合切除术。通过回顾医院和临床数据收集手术细节和早期结果。

结果

第1组患者的平均年龄为6.73±1.1个月,第2组为6.76±1.2个月,平均体重分别为6.01±1.3千克和5.9±1.0千克。两组术中及术后变量之间无显著差异。第1组有6例患者的收缩期峰值梯度>20mmHg。第1组的复发率为12%,第2组为1.8%(p<0.05)。总死亡率为2.8%。第1组的生存率为96%,第2组为98.2%。

结论

婴儿期主动脉缩窄采用端到端吻合切除术修复,死亡率低,再缩窄发生率低,为婴儿期主动脉缩窄提供了最佳预后。

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