低剂量克伦特罗中毒病例。
Case of low dose clenbuterol toxicity.
作者信息
Waight Michael, McGuinness William
机构信息
St George's Hospital, London, UK.
Department of A&E, St George's Hospital, London, UK.
出版信息
BMJ Case Rep. 2016 Apr 15;2016:10.1136/bcr-2016-215157. doi: 10.1136/bcr-2016-215157.
Abstract
We present a case of acute clenbuterol toxicity following ingestion of 20 μg of clenbuterol, resulting in symptoms of sympathetic activation, sinus tachycardia and electrolyte derangement. The patient was managed conservatively with fluid resuscitation, electrolyte replacement and monitoring, and discharged following a 5-day stay in hospital.
摘要
我们报告一例摄入20微克克伦特罗后发生急性克伦特罗中毒的病例，出现了交感神经兴奋、窦性心动过速和电解质紊乱症状。患者通过液体复苏、电解质补充和监测进行保守治疗，住院5天后出院。
相似文献
1
Case of low dose clenbuterol toxicity.低剂量克伦特罗中毒病例。
BMJ Case Rep. 2016 Apr 15;2016:10.1136/bcr-2016-215157. doi: 10.1136/bcr-2016-215157.
2
Clenbuterol ingestion causing prolonged tachycardia, hypokalemia, and hypophosphatemia with confirmation by quantitative levels.摄入克仑特罗导致持续性心动过速、低钾血症和低磷血症，并经定量检测得以证实。
J Toxicol Clin Toxicol. 2001;39(4):339-44. doi: 10.1081/clt-100105152.
3
Acute clenbuterol overdose resulting in supraventricular tachycardia and atrial fibrillation.急性克仑特罗过量导致室上性心动过速和心房颤动。
J Med Toxicol. 2007 Jun;3(2):56-60. doi: 10.1007/BF03160909.
4
Acute clenbuterol overdose manifestations in a suicide attempt--a case report.自杀未遂中急性克伦特罗过量表现——病例报告
Pol Merkur Lekarski. 2015 Dec;39(234):379-81.
5
Acute poisoning with clenbuterol--a case report.克仑特罗急性中毒——病例报告
Przegl Lek. 1997;54(10):763-4.
6
Clenbuterol: a new toxic substance in paediatrics.克仑特罗：儿科领域的一种新型有毒物质。
BMJ Case Rep. 2020 Mar 12;13(3):e233180. doi: 10.1136/bcr-2019-233180.
7
Food poisoning by clenbuterol in Portugal.葡萄牙发生的克伦特罗食物中毒事件。
Food Addit Contam. 2005 Jun;22(6):563-6. doi: 10.1080/02652030500135102.
8
A Case Series of Clenbuterol Toxicity Caused by Adulterated Heroin.一例因掺假海洛因导致的克仑特罗中毒病例系列报道
J Emerg Med. 2016 Sep;51(3):259-61. doi: 10.1016/j.jemermed.2016.05.047. Epub 2016 Jul 16.
9
Myocardial ischemia associated with clenbuterol abuse: report of two cases.与克仑特罗滥用相关的心肌缺血：两例报告
J Emerg Med. 2013 Feb;44(2):444-9. doi: 10.1016/j.jemermed.2012.02.057. Epub 2012 May 24.
10
[Adrenergic beta-agonist intoxication].[肾上腺素能β受体激动剂中毒]
Acta Med Port. 2003 Jul-Aug;16(4):275-8.
引用本文的文献
1
Low Dose Clenbuterol Toxicity: Case Report and Review of Literature.低剂量克仑特罗中毒：病例报告及文献综述
HCA Healthc J Med. 2020 Aug 29;1(4):201-204. doi: 10.36518/2689-0216.1086. eCollection 2020.
2
Adverse events of clenbuterol among athletes: a systematic review of case reports and case series.运动员使用克仑特罗的不良事件：病例报告和病例系列的系统评价。
Int J Legal Med. 2023 Jul;137(4):1023-1037. doi: 10.1007/s00414-023-02996-1. Epub 2023 Apr 17.
3
Changes in Health-related Parameters Associated with Sports Performance Enhancement Drugs.与运动表现增强药物相关的健康相关参数的变化。
Int J Sports Med. 2023 Mar;44(3):206-214. doi: 10.1055/a-1960-2543. Epub 2022 Dec 2.
4
Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein.β2-肾上腺素能受体激动剂克仑特罗可使α-突触核蛋白mRNA短暂减少，但不会使蛋白质长期减少。
NPJ Parkinsons Dis. 2022 May 24;8(1):61. doi: 10.1038/s41531-022-00322-x.
5
Clenbuterol-induced myocarditis in a young man desiring to lose weight.年轻男性为减肥使用克仑特罗致心肌炎。
BMJ Case Rep. 2022 Mar 14;15(3):e247898. doi: 10.1136/bcr-2021-247898.
本文引用的文献
1
Effect of clenbuterol on apoptosis, adipogenesis, and lipolysis in adipocytes.克仑特罗对脂肪细胞凋亡、脂肪生成和脂解的影响。
J Physiol Biochem. 2010 Sep;66(3):197-203. doi: 10.1007/s13105-010-0024-8. Epub 2010 Jun 10.
2
Acute clenbuterol overdose resulting in supraventricular tachycardia and atrial fibrillation.急性克仑特罗过量导致室上性心动过速和心房颤动。
J Med Toxicol. 2007 Jun;3(2):56-60. doi: 10.1007/BF03160909.
3
Food-borne clenbuterol may have potential for cardiovascular effects with chronic exposure (commentary).
J Toxicol Clin Toxicol. 2001;39(4):345-8. doi: 10.1081/clt-100105153.
4
Clenbuterol ingestion causing prolonged tachycardia, hypokalemia, and hypophosphatemia with confirmation by quantitative levels.摄入克仑特罗导致持续性心动过速、低钾血症和低磷血症，并经定量检测得以证实。
J Toxicol Clin Toxicol. 2001;39(4):339-44. doi: 10.1081/clt-100105152.
5
beta-adrenergic receptor blockade in chronic heart failure.慢性心力衰竭中的β-肾上腺素能受体阻滞剂
Circulation. 2000 Feb 8;101(5):558-69. doi: 10.1161/01.cir.101.5.558.
6
7
Clenbuterol: a substitute for anabolic steroids?克仑特罗：合成代谢类固醇的替代品？
Med Sci Sports Exerc. 1995 Aug;27(8):1118-21.
8
Bronchodilating and cardiovascular effects of intraduodenally and orally administered clenbuterol in dogs.犬经十二指肠和口服给予克伦特罗后的支气管扩张及心血管效应
Arzneimittelforschung. 1985;35(7):1037-41.
9
Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation.
Am J Physiol. 1992 Jul;263(1 Pt 1):E50-6. doi: 10.1152/ajpendo.1992.263.1.E50.
Zotero 插件