• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

气道相关问题儿童的口咽24小时pH监测

Oropharyngeal 24-Hour pH Monitoring in Children With Airway-Related Problems.

作者信息

Mesallam Tamer A

机构信息

Department of Otorhinolaryngology, King Abdulaziz University Hospital, King Saud University College of Medicine, Research Chair of Voice, Swallowing, and Communication Disorders, Riyadh, Saudi Arabia, Egypt.

Department of Otorhinolaryngology, Menoufiya University College of Medicine, Shebin Alkoum, Egypt.

出版信息

Clin Exp Otorhinolaryngol. 2016 Jun;9(2):168-72. doi: 10.21053/ceo.2015.00409. Epub 2016 Apr 19.

DOI:10.21053/ceo.2015.00409
PMID:27090271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4881324/
Abstract

OBJECTIVES

Diagnosis and clinical presentation of pediatric laryngopharyngeal reflux (LPR) is still controversial. The aims of this work were to study the possibility of performing 24-hour oropharyngeal pH monitoring for children in the outpatient clinic setup and to explore the results of this test in correlation to airway-related problems.

METHODS

In this descriptive qualitative study, 26 children suffering from airway-related problems were included. Oropharyngeal 24-hour pH monitoring was performed for all subjects in the outpatient clinic setting. The distribution of airway diagnoses among the study group was studied versus the results of the pH monitoring.

RESULTS

There were 16 males and 10 females participated in the study with a mean age of 6.88 (SD, ±5.77) years. Thirty-five percent of the patients were under the age of 3 years (range, 11 months to 3 years). Eight-five percent of the patients tolerated the pH probe insertion and completed 24-hour of pH recording. Laryngomalacia and subglottic stenosis (SGS) were more frequently reported in the positive LPR patients (77%).

CONCLUSION

Oropharyngeal 24-hour pH monitoring can be conducted for children in the outpatient setup even in young age children below 3 years old. Among the positive LPR group, SGS and laryngomalacia were the most commonly reported airway findings.

摘要

目的

小儿喉咽反流(LPR)的诊断和临床表现仍存在争议。本研究的目的是探讨在门诊环境下对儿童进行24小时口咽pH监测的可能性,并探讨该测试结果与气道相关问题的相关性。

方法

在这项描述性定性研究中,纳入了26名患有气道相关问题的儿童。在门诊环境中对所有受试者进行口咽24小时pH监测。研究了研究组中气道诊断的分布情况与pH监测结果的关系。

结果

共有16名男性和10名女性参与研究,平均年龄为6.88(标准差,±5.77)岁。35%的患者年龄在3岁以下(范围为11个月至3岁)。85%的患者耐受pH探头插入并完成了24小时的pH记录。在LPR阳性患者中,喉软化和声门下狭窄(SGS)的报告更为频繁(77%)。

结论

即使是3岁以下的幼儿,也可以在门诊环境中对儿童进行口咽24小时pH监测。在LPR阳性组中,SGS和喉软化是最常报告的气道发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9392/4881324/5470e4f5c407/ceo-2015-00409f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9392/4881324/d574aa4a8082/ceo-2015-00409f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9392/4881324/5470e4f5c407/ceo-2015-00409f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9392/4881324/d574aa4a8082/ceo-2015-00409f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9392/4881324/5470e4f5c407/ceo-2015-00409f2.jpg

相似文献

1
Oropharyngeal 24-Hour pH Monitoring in Children With Airway-Related Problems.气道相关问题儿童的口咽24小时pH监测
Clin Exp Otorhinolaryngol. 2016 Jun;9(2):168-72. doi: 10.21053/ceo.2015.00409. Epub 2016 Apr 19.
2
[Correlation analysis between Dx-pH monitoring and proton pump inhibitor test in the diagnosis of laryngopharyngeal reflux disease].[Dx-pH监测与质子泵抑制剂试验在喉咽反流性疾病诊断中的相关性分析]
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan 7;55(1):34-39. doi: 10.3760/cma.j.issn.1673-0860.2020.01.007.
3
Self-Perception of Swallowing-Related Problems in Laryngopharyngeal Reflux Patients Diagnosed with 24-Hour Oropharyngeal pH Monitoring.经24小时口咽pH监测诊断的喉咽反流患者对吞咽相关问题的自我认知。
Biomed Res Int. 2016;2016:7659016. doi: 10.1155/2016/7659016. Epub 2016 Feb 4.
4
Voice problems among laryngopharyngeal reflux patients diagnosed with oropharyngeal pH monitoring.经口咽pH监测诊断的喉咽反流患者的嗓音问题。
Folia Phoniatr Logop. 2013;65(6):280-7. doi: 10.1159/000362835. Epub 2014 May 24.
5
Association of laryngopharyngeal reflux disease and subglottic stenosis.喉咽反流病与声门下狭窄的关联
Ann Otol Rhinol Laryngol. 2001 Jul;110(7 Pt 1):606-12. doi: 10.1177/000348940111000703.
6
Diagnosis of laryngopharyngeal reflux in children with voice disorders using 24-hour pharyngeal pH monitoring.采用24小时咽pH监测诊断嗓音障碍儿童的喉咽反流。
Int J Pediatr Otorhinolaryngol. 2019 Jun;121:188-196. doi: 10.1016/j.ijporl.2019.03.010. Epub 2019 Mar 14.
7
Wireless 24, 48, and 96 Hour or Impedance or Oropharyngeal Prolonged pH Monitoring: Which Test, When, and Why for GERD?无线24小时、48小时和96小时监测或阻抗监测或口咽长时间pH监测:对于胃食管反流病,选择哪种检测、何时检测以及为何检测?
Curr Gastroenterol Rep. 2018 Sep 26;20(11):52. doi: 10.1007/s11894-018-0659-0.
8
Relationship between extralaryngeal endoscopic findings, proton pump inhibitor (PPI) response, and pH measures in suspected laryngopharyngeal reflux.疑似喉咽反流中喉内镜检查结果、质子泵抑制剂(PPI)反应与 pH 值测量的关系。
Dis Esophagus. 2019 Apr 1;32(4). doi: 10.1093/dote/doy072.
9
Correlation between oropharyngeal pH-monitoring and esophageal pH-impedance monitoring in patients with suspected GERD-related extra-esophageal symptoms.疑似胃食管反流病相关食管外症状患者口咽pH监测与食管pH阻抗监测的相关性
Neurogastroenterol Motil. 2014 Nov;26(11):1557-64. doi: 10.1111/nmo.12422. Epub 2014 Sep 10.
10
Laryngopharyngeal Reflux in Children with Chronic Otitis Media with Effusion.伴有积液的慢性中耳炎患儿的喉咽反流
J Neurogastroenterol Motil. 2016 Jul 30;22(3):452-8. doi: 10.5056/jnm16013.

引用本文的文献

1
Determination of pepsin in human saliva using pepsin-susceptible peptide reporter and colorimetric dipstick assay: a prospective, cross-sectional study.采用对胃蛋白酶敏感的肽报告物和比色检测棒法测定人唾液中的胃蛋白酶:一项前瞻性、横断面研究。
Mikrochim Acta. 2024 Jan 31;191(2):117. doi: 10.1007/s00604-024-06192-9.
2
[New progress in diagnosis and treatment of congenital laryngomalacia in infants].[婴儿先天性喉软化症的诊断与治疗新进展]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Dec;37(12):982-985. doi: 10.13201/j.issn.2096-7993.2023.12.011.
3
Pediatric Laryngopharyngeal Reflux: An Evidence-Based Review.

本文引用的文献

1
Histologic versus pH probe results in pediatric laryngopharyngeal reflux.小儿喉咽反流的组织学与pH探针检测结果对比
Int J Pediatr Otorhinolaryngol. 2013 May;77(5):813-6. doi: 10.1016/j.ijporl.2013.02.017. Epub 2013 Mar 13.
2
A systematic review of laryngomalacia and acid reflux.喉软化症与胃酸反流的系统评价
Otolaryngol Head Neck Surg. 2012 Oct;147(4):619-26. doi: 10.1177/0194599812452833. Epub 2012 Jun 27.
3
Tracheal pH monitoring: a pilot study in tracheostomy dependent children.
小儿喉咽反流:循证综述
Children (Basel). 2023 Mar 18;10(3):583. doi: 10.3390/children10030583.
4
Pediatric Laryngopharyngeal Reflux in the Last Decade: What Is New and Where to Next?过去十年的小儿喉咽反流:新进展与未来方向?
J Clin Med. 2023 Feb 10;12(4):1436. doi: 10.3390/jcm12041436.
5
Gastroesophageal Reflux in Children with Asthma.哮喘儿童的胃食管反流
Children (Basel). 2022 Mar 2;9(3):336. doi: 10.3390/children9030336.
6
Optimization of Saliva Collection and Immunochromatographic Detection of Salivary Pepsin for Point-of-Care Testing of Laryngopharyngeal Reflux.优化唾液采集和免疫层析法检测唾液胃蛋白酶用于即时检测咽喉反流
Sensors (Basel). 2020 Jan 6;20(1):325. doi: 10.3390/s20010325.
Int J Pediatr Otorhinolaryngol. 2009 Jul;73(7):999-1001. doi: 10.1016/j.ijporl.2009.04.002. Epub 2009 May 13.
4
Oropharyngeal pH monitoring for the detection of liquid and aerosolized supraesophageal gastric reflux.用于检测液体和雾化食管上胃反流的口咽pH监测
J Voice. 2009 Jul;23(4):498-504. doi: 10.1016/j.jvoice.2007.12.005. Epub 2008 May 12.
5
Multilevel esophageal biopsy in children with airway manifestations of extraesophageal reflux disease.
Ann Otol Rhinol Laryngol. 2007 Aug;116(8):571-5. doi: 10.1177/000348940711600803.
6
Diagnostic and management problems of laryngopharyngeal reflux disease in children.儿童喉咽反流疾病的诊断与管理问题
Int J Pediatr Otorhinolaryngol. 2006 Apr;70(4):579-90. doi: 10.1016/j.ijporl.2005.10.021. Epub 2005 Dec 15.
7
Predictive value of laryngeal pseudosulcus for gastroesophageal reflux in pediatric patients.
Int J Pediatr Otorhinolaryngol. 2005 Aug;69(8):1109-12. doi: 10.1016/j.ijporl.2005.02.022.
8
Meta-analysis of upper probe measurements in normal subjects and patients with laryngopharyngeal reflux.正常受试者和喉咽反流患者上探头测量的荟萃分析。
Ann Otol Rhinol Laryngol. 2005 Mar;114(3):177-82. doi: 10.1177/000348940511400302.
9
Transforming growth factor-beta1, myofibroblasts, and tissue remodeling in the pathogenesis of tracheal injury: potential role of gastroesophageal reflux.转化生长因子-β1、肌成纤维细胞与气管损伤发病机制中的组织重塑:胃食管反流的潜在作用
Ann Otol Rhinol Laryngol. 2004 Jun;113(6):488-97. doi: 10.1177/000348940411300614.
10
The role of 24 h pH-recording in pediatric otolaryngologic gastro-esophageal reflux disease.24小时pH监测在小儿耳鼻咽喉科胃食管反流病中的作用
Int J Pediatr Otorhinolaryngol. 2003 Dec;67 Suppl 1:S95-100. doi: 10.1016/j.ijporl.2003.08.038.