Vo Quynh T, Hoffman Susie, Nash Denis, El-Sadr Wafaa M, Tymejczyk Olga A, Gadisa Tsigereda, Melaku Zenebe, Kulkarni Sarah G, Remien Robert H, Elul Batya
ICAP-Columbia University, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY, 10032, USA.
HIV Center for Clinical and Behavioral Studies at the NYS Psychiatric Institute, Columbia University, New York, USA.
AIDS Behav. 2016 Aug;20(8):1682-91. doi: 10.1007/s10461-016-1396-8.
Health-related quality of life (HRQoL) is an important outcome to assess among persons living with HIV/AIDS, but few studies have been conducted in sub-Saharan Africa. We examined HRQoL among 1180 ART-initiating adults from six clinics in Ethiopia in 2012-2013, and compared the correlates of two subscale scores between women and men. Women scored significantly higher than men on both overall function (8.4 points higher) and life satisfaction (6.3 points higher). In multivariable models, psychological distress, low CD4+ count, unemployment, and food insecurity were associated with lower quality of life scores among women and men. Men whose last sexual encounter occurred 3 months to 1 year from the interview date had lower overall function and life satisfaction scores. Men between the ages of 30-39 had lower overall function scores. Protestant women and women in the low-middle social support category had lower life satisfaction scores. Assessment of HRQoL over time will help inform HIV care and treatment practices to ensure favorable patient outcomes.
与健康相关的生活质量（HRQoL）是评估艾滋病毒/艾滋病感染者的一项重要指标，但在撒哈拉以南非洲地区开展的相关研究较少。2012年至2013年，我们对埃塞俄比亚六家诊所的1180名开始接受抗逆转录病毒治疗（ART）的成年人的健康相关生活质量进行了调查，并比较了男女两组在两个分量表得分上的相关因素。在总体功能（高出8.4分）和生活满意度（高出6.3分）方面，女性得分均显著高于男性。在多变量模型中，心理困扰、低CD4 +计数、失业和粮食不安全与男女生活质量得分较低相关。上次性接触发生在距访谈日期3个月至1年之间的男性，其总体功能和生活满意度得分较低。年龄在30至39岁之间的男性总体功能得分较低。新教女性和社会支持处于中低水平的女性生活满意度得分较低。长期评估健康相关生活质量将有助于为艾滋病毒护理和治疗实践提供信息，以确保患者获得良好的治疗效果。
