Nagaraja H S, Jeganathan P S
Department of Physiology, Kasturba Medical College, Mangalore - 575 001.
Indian J Physiol Pharmacol. 1999 Jan;43(1):53-9.
The effects of fresh water swimming and cold water swimming for one day, 7 days and 15 days were studied on the total body weight, weight of the heart, kidney, adrenals, blood sugar level, serum cholesterol level, total leucocyte count, absolute neutrophil count and absolute eosinophil count in albino rats. The stress session in each day lasted for 45 min. Though the body weight of the animals decreased significantly during the initial period, when the stress period was prolonged, there was recovery in the body weight. There was a significant increase in the weight of the heart, kidney and adrenal glands after both types of stress. A significant leucopenia, eosinopenia and neutropenia along with significant hypoglycemia and hypocholesterolemia was observed in all the subgroups. A maximum stress response was seen upto a period of 7 days and the stress response decreased when the stress period was prolonged to 15 days in the physiological parameters studied. This could be due to the adaptation or habituation for the continued stress. There was no sign of adaptation in the case of biochemical parameters studied. A statistically significant physiological and biochemical changes were observed even after one day of forced swimming stress.
研究了白化大鼠进行一天、7天和15天的淡水游泳和冷水游泳对其体重、心脏、肾脏、肾上腺重量、血糖水平、血清胆固醇水平、白细胞总数、绝对中性粒细胞计数和绝对嗜酸性粒细胞计数的影响。每天的应激时段持续45分钟。虽然在初始阶段动物体重显著下降，但当应激期延长时，体重出现恢复。两种应激后心脏、肾脏和肾上腺的重量均显著增加。在所有亚组中均观察到显著的白细胞减少、嗜酸性粒细胞减少和中性粒细胞减少，以及显著的低血糖和低胆固醇血症。在所研究的生理参数中，在7天的时间段内观察到最大应激反应，当应激期延长至15天时，应激反应降低。这可能是由于对持续应激的适应或习惯。在所研究的生化参数方面没有适应迹象。即使在强迫游泳应激一天后，也观察到了具有统计学意义的生理和生化变化。
