颞叶癫痫患者胼胝体的平面测量研究
Planimetry investigation of the corpus callosum in temporal lobe epilepsy patients.
作者信息
Caglar Veli, Alp Selen I, Demir Berrin T, Sener Umit, Ozen Oguz A, Alp Recep
机构信息
Departments of Anatomy, Faculty of Medicine, Namik Kemal University, Tekirdag, Turkey.
出版信息
Neurosciences (Riyadh). 2016 Apr;21(2):145-50. doi: 10.17712/nsj.2016.2.20150783.
OBJECTIVE
To evaluate the effects of temporal lobe epilepsy (TLE) on corpus callosum (CC) morphometry in patients with TLE.
METHODS
This retrospective study was conducted at the Faculty of Medicine, Tekirdag Namik Kemal University, Tekirdag, Turkey between November 2010 and December 2013. The epileptic syndrome diagnosis was based on International League Against Epilepsy criteria, and this study was conducted on the MRIs of 25 epilepsy patients and 25 control subjects. We classified the patients according to their duration of epilepsy: <10 and >/=10 years. The projection area length (PAL) of the CC was also estimated. Total brain volumes (TBV) were measured on CT images.
RESULTS
The mean values of TBV for patients with TLE and the control group were not statistically different, but the CC PAL values were statistically different. The mean CC PAL values of under and over 25 years of age in patients with TLE were statistically different. The mean values of TBV of under and over 10 years duration of TLE were small statistically, but the CC PAL values were statistically different.
CONCLUSION
The results indicate a clear influence of TLE on the structure of the CC rather than TBV.
目的
评估颞叶癫痫（TLE）对TLE患者胼胝体（CC）形态测量的影响。
方法
这项回顾性研究于2010年11月至2013年12月在土耳其泰基尔达的泰基尔达纳米克·凯末尔大学医学院进行。癫痫综合征诊断基于国际抗癫痫联盟标准，本研究对25例癫痫患者和25例对照受试者的磁共振成像（MRI）进行。我们根据癫痫持续时间对患者进行分类：<10年和≥10年。还估计了CC的投射区长度（PAL）。在计算机断层扫描（CT）图像上测量全脑体积（TBV）。
结果
TLE患者和对照组的TBV平均值无统计学差异，但CC PAL值有统计学差异。TLE患者中25岁以下和25岁以上的平均CC PAL值有统计学差异。TLE持续时间<10年和≥10年的TBV平均值有微小统计学差异，但CC PAL值有统计学差异。
结论
结果表明TLE对CC结构有明显影响，而非对TBV有明显影响。
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