Krishnamurthy Arvind, Ramshankar Vijayalakshmi, Majhi Urmila
Department of Surgical Oncology, Pathology Cancer Institute, Chennai, Tamil Nadu, India.
Department of Preventive Oncology, Pathology Cancer Institute, Chennai, Tamil Nadu, India.
Indian J Nucl Med. 2016 Apr-Jun;31(2):128-30. doi: 10.4103/0972-3919.178264.
Pulmonary mucoepidermoid carcinoma (PMEC) is a rare tumor of bronchial gland origin with a striking resemblance to MEC of the salivary glands. The World Health Organization classifies PMECs as "salivary gland type" tumors along with pulmonary adenoid cystic carcinomas and epimyoepithelial lung carcinomas. Their description in literature is largely limited to a few case series/case reports. Further, the experience of imaging in these tumors with fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography ( (18)F-FDG PET-CT) is also limited and evolving largely due to rarity of PMEC. We recently managed an interesting case of a PMEC and reviewed the literature surrounding this rare tumor with an emphasis on the role of (18)F-FDG PET-CT in its management. An (18)F-FDG PET-CT appears to be a useful imaging modality for predicting the tumor grade of patients with PMECs; further, there is emerging data to suggest the role of (18)F-FDG PET-CT for predicting the long-term prognosis of patients with PMEC.
肺黏液表皮样癌(PMEC)是一种起源于支气管腺体的罕见肿瘤,与涎腺黏液表皮样癌极为相似。世界卫生组织将PMEC与肺腺样囊性癌和肺上皮肌上皮癌一起归类为“涎腺型”肿瘤。文献中对它们的描述主要局限于少数病例系列/病例报告。此外,由于PMEC罕见,关于这些肿瘤的氟-18氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描((18)F-FDG PET-CT)成像经验也有限且仍在不断发展。我们最近处理了一例有趣的PMEC病例,并回顾了围绕这种罕见肿瘤的文献,重点关注(18)F-FDG PET-CT在其治疗中的作用。(18)F-FDG PET-CT似乎是预测PMEC患者肿瘤分级的一种有用成像方式;此外,越来越多的数据表明(18)F-FDG PET-CT在预测PMEC患者长期预后方面的作用。