Wiggins Richard H, Hoffman John M, Fine Gabriel C, Covington Matthew F, Salem Ahmed Ebada, Koppula Bhasker R, Morton Kathryn A
Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT 84132, USA.
Department of Radiodiagnosis and Intervention, Faculty of Medicine, Alexandria University, Alexandria 21526, Egypt.
Cancers (Basel). 2022 May 31;14(11):2726. doi: 10.3390/cancers14112726.
PET-CT is an advanced imaging modality with many oncologic applications, including staging, assessment of response to therapy, restaging, and longitudinal surveillance for recurrence. The goal of this series of six review articles is to provide practical information to providers and imaging professionals regarding the best use of PET-CT for specific oncologic indications, and the potential pitfalls and nuances that characterize these applications. In addition, key tumor-specific clinical information and representative PET-CT images are provided to outline the role that PET-CT plays in the management of oncology patients. Hundreds of different types of tumors exist, both pediatric and adult. A discussion of the role of FDG PET for all of these is beyond the scope of this review. Rather, this series of articles focuses on the most common adult malignancies that may be encountered in clinical practice. It also focuses on FDA-approved and clinically available radiopharmaceuticals, rather than research tracers or those requiring a local cyclotron. The fifth review article in this series focuses on PET-CT imaging in head and neck tumors, as well as brain tumors. Common normal variants, key anatomic features, and benign mimics of these tumors are reviewed. The goal of this review article is to provide the imaging professional with guidance in the interpretation of PET-CT for the more common head and neck malignancies and neuro oncology, and to inform the referring providers so that they can have realistic expectations of the value and limitations of PET-CT for the specific type of tumor being addressed.
正电子发射断层显像-X线计算机体层成像（PET-CT）是一种先进的成像方式，在肿瘤学领域有诸多应用，包括分期、评估治疗反应、再分期以及对复发情况进行长期监测。这一系列六篇综述文章的目的是为医疗服务提供者和影像专业人员提供实用信息，内容涉及PET-CT在特定肿瘤学适应证中的最佳应用，以及这些应用所具有的潜在陷阱和细微差别。此外，还提供了关键的肿瘤特异性临床信息和具有代表性的PET-CT图像，以概述PET-CT在肿瘤患者管理中所起的作用。存在数百种不同类型的肿瘤，涵盖儿童和成人肿瘤。对FDG PET在所有这些肿瘤中的作用进行讨论超出了本综述的范围。相反，这一系列文章聚焦于临床实践中可能遇到的最常见成人恶性肿瘤。它还聚焦于美国食品药品监督管理局（FDA）批准且临床可用的放射性药物，而非研究用示踪剂或那些需要本地回旋加速器的药物。本系列的第五篇综述文章聚焦于头颈部肿瘤以及脑肿瘤的PET-CT成像。对这些肿瘤常见的正常变异、关键解剖特征以及良性假象进行了综述。这篇综述文章的目的是为影像专业人员提供解读PET-CT用于更常见头颈部恶性肿瘤和神经肿瘤学方面的指导，并告知转诊的医疗服务提供者，以便他们能对PET-CT针对所讨论的特定类型肿瘤的价值和局限性有切合实际的预期。
