Bian Yun, Wang Zhi Xiong, Han Xiao Le, Chen Li, Zhu Yu, Wu Cheng Jing
Department of Psychosomatic Medicine, Beijing HuiLongGuan Hospital, Peking University, Beijing 100096, PR China.
Department of Psychology, Beijing HuiLongGuan Hospital, Peking University, Beijing 100096, PR China.
Compr Psychiatry. 2016 May;67:33-8. doi: 10.1016/j.comppsych.2016.02.008. Epub 2016 Feb 18.
This study investigates subjective and objective sleep quality to ascertain whether there is a sleep state misperception in schizophrenia patients, as well as analyze potential effect factors.
A total of 148 inpatients with schizophrenia admitted to Beijing HuiLongGuan Hospital were enrolled in this study. The quality of objective sleep was assessed by polysomnography (PSG). On the second day after the successful completion of the PSG evaluation, an interview was arranged to collect patients' recorded subjective evaluation on sleep time, sleep latency, and wake times. Demographic information was collected from an interview, medical records were reviewed, and psychiatric symptoms were assessed using the Positive And Negative Symptom Scale (PANSS).
The main finding of this study was that schizophrenic patients exhibited sleep state misperception with a pattern of overestimation of total sleep time (TST) as well as sleep efficiency (SE), and an underestimation of sleep onset latency (SOL). Regarding the ±standard deviation of the differences between subjective and objective TST as a clinical acceptable range, the patients were divided into three groups: the overestimate group, the normal group, and the underestimate group. The differences of total PANSS score, especially the PANSS-N score in the overestimate group, the normal group and the underestimate group were significant, and there were significant differences between the overestimate group and the other groups.
A comprehensive evaluation of the subjective and objective sleep quality in patients with schizophrenia is needed, especially when negative symptoms are severe.
本研究调查主观和客观睡眠质量，以确定精神分裂症患者是否存在睡眠状态误判，并分析潜在影响因素。
本研究纳入了148名在北京回龙观医院住院的精神分裂症患者。通过多导睡眠图（PSG）评估客观睡眠质量。在PSG评估成功完成后的第二天，安排访谈以收集患者对睡眠时间、睡眠潜伏期和觉醒次数的记录主观评价。通过访谈收集人口统计学信息，查阅病历，并使用阳性和阴性症状量表（PANSS）评估精神症状。
本研究的主要发现是，精神分裂症患者表现出睡眠状态误判，其模式为高估总睡眠时间（TST）和睡眠效率（SE），低估睡眠起始潜伏期（SOL）。以主观和客观TST之间差异的±标准差作为临床可接受范围，将患者分为三组：高估组、正常组和低估组。高估组、正常组和低估组的PANSS总分差异显著，尤其是PANSS-N得分，高估组与其他组之间存在显著差异。
需要对精神分裂症患者的主观和客观睡眠质量进行综合评估，尤其是在阴性症状严重时。
