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患者自评主观全面评定简表(PG-SGA SF)是化疗门诊患者有效的筛查工具。

Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF) is a valid screening tool in chemotherapy outpatients.

作者信息

Abbott Jessica, Teleni L, McKavanagh D, Watson J, McCarthy A L, Isenring E

机构信息

Gold Coast University Hospital, Southport, QLD, 4215, Australia.

Princess Alexandra Hospital, Woolloongabba, QLD, 4102, Australia.

出版信息

Support Care Cancer. 2016 Sep;24(9):3883-7. doi: 10.1007/s00520-016-3196-0. Epub 2016 Apr 19.

Abstract

PURPOSE

In the oncology population where malnutrition prevalence is high, more descriptive screening tools can provide further information to assist triaging and capture acute change. The Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF) is a component of a nutritional assessment tool which could be used for descriptive nutrition screening. The purpose of this study was to conduct a secondary analysis of nutrition screening and assessment data to identify the most relevant information contributing to the PG-SGA SF to identify malnutrition risk with high sensitivity and specificity.

METHODS

This was an observational, cross-sectional study of 300 consecutive adult patients receiving ambulatory anti-cancer treatment at an Australian tertiary hospital. Anthropometric and patient descriptive data were collected. The scored PG-SGA generated a score for nutritional risk (PG-SGA SF) and a global rating for nutrition status. Receiver operating characteristic curves (ROC) were generated to determine optimal cut-off scores for combinations of the PG-SGA SF boxes with the greatest sensitivity and specificity for predicting malnutrition according to scored PG-SGA global rating.

RESULTS

The additive scores of boxes 1-3 had the highest sensitivity (90.2 %) while maintaining satisfactory specificity (67.5 %) and demonstrating high diagnostic value (AUC = 0.85, 95 % CI = 0.81-0.89). The inclusion of box 4 (PG-SGA SF) did not add further value as a screening tool (AUC = 0.85, 95 % CI = 0.80-0.89; sensitivity 80.4 %; specificity 72.3 %).

CONCLUSIONS

The validity of the PG-SGA SF in chemotherapy outpatients was confirmed. The present study however demonstrated that the functional capacity question (box 4) does not improve the overall discriminatory value of the PG-SGA SF.

摘要

目的

在营养不良患病率较高的肿瘤患者群体中,更多具有描述性的筛查工具能够提供更多信息,以辅助进行分诊并捕捉急性变化。患者主观全面评定简表(PG-SGA SF)是一种营养评估工具的组成部分,可用于描述性营养筛查。本研究的目的是对营养筛查和评估数据进行二次分析,以确定对PG-SGA SF最具相关性的信息,从而以高灵敏度和特异性识别营养不良风险。

方法

这是一项对澳大利亚一家三级医院300例接受门诊抗癌治疗的成年患者进行的观察性横断面研究。收集了人体测量和患者描述性数据。计分的PG-SGA得出营养风险评分(PG-SGA SF)和营养状况总体评定。绘制受试者工作特征曲线(ROC),以确定根据计分的PG-SGA总体评定,预测营养不良时具有最高灵敏度和特异性的PG-SGA SF各部分组合的最佳截断分数。

结果

第1 - 3部分的累加分数具有最高灵敏度(90.2%),同时保持了令人满意的特异性(67.5%),并显示出较高的诊断价值(AUC = 0.85,95% CI = 0.81 - 0.89)。纳入第4部分(PG-SGA SF)作为筛查工具并未增加更多价值(AUC = 0.85,95% CI = 0.80 - 0.89;灵敏度80.4%;特异性72.3%)。

结论

PG-SGA SF在化疗门诊患者中的有效性得到了证实。然而,本研究表明功能能力问题(第4部分)并未提高PG-SGA SF的总体鉴别价值。

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