Voelker Maximilian N, Kraff Oliver, Brenner Daniel, Wollrab Astrid, Weinberger Oliver, Berger Moritz C, Robinson Simon, Bogner Wolfgang, Wiggins Christopher, Trampel Robert, Stöcker Tony, Niendorf Thoralf, Quick Harald H, Norris David G, Ladd Mark E, Speck Oliver
Erwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen, Kokereiallee 7, 45141, Essen, Germany.
German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
MAGMA. 2016 Jun;29(3):399-415. doi: 10.1007/s10334-016-0541-8. Epub 2016 Apr 20.
This study evaluates the inter-site and intra-site reproducibility of 7 Tesla brain imaging and compares it to literature values for other field strengths.
The same two subjects were imaged at eight different 7 T sites. MP2RAGE, TSE, TOF, SWI, EPI as well as B1 and B0 field maps were analyzed quantitatively to assess inter-site reproducibility. Intra-site reproducibility was measured with rescans at three sites.
Quantitative measures of MP2RAGE scans showed high agreement. Inter-site and intra-site reproducibility errors were comparable to 1.5 and 3 T. Other sequences also showed high reproducibility between the sites, but differences were also revealed. The different RF coils used were the main source for systematic differences between the sites.
Our results show for the first time that multi-center brain imaging studies of the supratentorial brain can be performed at 7 T with high reproducibility and similar reliability as at 3T. This study develops the basis for future large-scale 7 T multi-site studies.
本研究评估7特斯拉脑成像的不同站点间和站点内的可重复性，并将其与其他场强的文献值进行比较。
对两名相同的受试者在八个不同的7T站点进行成像。对MP2RAGE、TSE、TOF、SWI、EPI以及B1和B0场图进行定量分析，以评估站点间的可重复性。在三个站点通过重新扫描测量站点内的可重复性。
MP2RAGE扫描的定量测量显示出高度一致性。站点间和站点内的可重复性误差与1.5T和3T时相当。其他序列在各站点间也显示出高可重复性，但也存在差异。所使用的不同射频线圈是各站点间系统差异的主要来源。
我们的结果首次表明，幕上脑的多中心脑成像研究可以在7T下进行，具有与3T时相当的高可重复性和相似的可靠性。本研究为未来大规模7T多站点研究奠定了基础。
