Jonsson J A, Eklund A, Molin L
Department of Toxicology, National Laboratory of Forensic Chemistry, University Hospital, Linköping, Sweden.
J Anal Toxicol. 1989 Jan-Feb;13(1):25-6. doi: 10.1093/jat/13.1.25.
A simple procedure for the determination of ethylene glycol in blood by capillary gas chromatography was developed. The proteins are precipitated by the addition of perchloric acid which includes the internal standard 1,2-butanediol. The extract is neutralized and the solution is directly injected. The assay is linear and the precision, expressed as coefficient of variation, is 4-11% (within run). The detection limit is about 0.05 g/L. The method also seems applicable for the determination of ethylene glycol in urine.
建立了一种用毛细管气相色谱法测定血液中乙二醇的简单方法。加入包含内标1,2 -丁二醇的高氯酸使蛋白质沉淀。提取物经中和后直接进样。该测定方法呈线性，以变异系数表示的精密度在批内为4 - 11%。检测限约为0.05 g/L。该方法似乎也适用于尿液中乙二醇的测定。
