Gibson Bradley, Podoll Mirna Bajramovic, Baumgartner Erin Marie, Maley Diana Haninger
Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, USA
Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, KY, USA.
Ann Clin Lab Sci. 2016 Spring;46(2):219-21.
Primary Hodgkin lymphoma of the gastrointestinal tract is an uncommon malignancy with few reported cases. Here we describe a rare variant of Hodgkin lymphoma presented in the gastrointestinal tract in association with Crohn's Disease.The patient is a 58 year old male with a 40 year history of formerly well-controlled Crohn's disease who presented with abdominal discomfort and constitutional symptoms. Computed tomography showed a 10 cm thickened segment of ileum and a dilated segment of small bowel. The patient underwent segmental resection, revealing a mass, which was diagnosed by pathology as nodular sclerosis classical Hodgkin lymphoma, syncytial variant.There are only 29 reported cases of syncytial variant of nodular sclerosis classical Hodgkin lymphoma. This is the second documented case of primary gastrointestinal syncytial variant of nodular sclerosis classical Hodgkin lymphoma. Further characterization of this entity is necessary.
原发性胃肠道霍奇金淋巴瘤是一种罕见的恶性肿瘤，报道的病例较少。在此，我们描述了1例与克罗恩病相关的胃肠道罕见霍奇金淋巴瘤变异型。患者为一名58岁男性，有40年曾得到良好控制的克罗恩病病史，因腹部不适和全身症状就诊。计算机断层扫描显示一段10厘米厚的回肠和一段扩张的小肠。患者接受了节段性切除，术中发现一个肿块，病理诊断为结节硬化型经典霍奇金淋巴瘤，合体细胞变异型。结节硬化型经典霍奇金淋巴瘤合体细胞变异型仅有29例报道。这是第二例有文献记录的原发性胃肠道结节硬化型经典霍奇金淋巴瘤合体细胞变异型。有必要对该实体进行进一步的特征描述。
