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全血科学现状:梅奥诊所的经验教训

The state of the science of whole blood: lessons learned at Mayo Clinic.

作者信息

Stubbs James R, Zielinski Martin D, Jenkins Donald

机构信息

Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine , Mayo Clinic Rochester, Rochester, New York.

Division of Trauma, Critical Care, and General Surgery, Mayo Clinic Rochester, Rochester, Minnesota.

出版信息

Transfusion. 2016 Apr;56 Suppl 2(Suppl 2):S173-81. doi: 10.1111/trf.13501.

DOI:10.1111/trf.13501
PMID:27100754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4882089/
Abstract

AABB Standards specify that ABO group-specific whole blood is the only acceptable choice for whole blood transfusions. Although universal donor group O stored whole blood (SWB) was used extensively by the military during the wars of the mid-twentieth century, its use has fallen out of favor and has never been used to great extent in the civilian trauma population. Interest in the use of whole blood has been renewed, particularly in light of its potential value in far-forward military and other austere environments. Evidence of preserved platelet function in SWB has heightened enthusiasm for a "one stop shop" resuscitation product providing volume, oxygen carrying capacity, and hemostatic effects. Experience with universal donor group O SWB is required to ascertain whether its use will be an advance in trauma care. Described here is the process of establishing a universal donor group O SWB at a civilian trauma center in the United States.

摘要

AABB标准规定,ABO血型特异性全血是全血输血唯一可接受的选择。尽管通用供血者O型储存全血(SWB)在20世纪中叶的战争期间被军队广泛使用,但其使用已不再受欢迎,并且在 civilian创伤人群中从未被广泛使用。对全血使用的兴趣已经重新燃起,特别是鉴于其在前沿军事和其他严峻环境中的潜在价值。SWB中保留的血小板功能的证据增强了人们对一种提供容量、携氧能力和止血效果的“一站式”复苏产品的热情。需要有通用供血者O型SWB的使用经验来确定其使用是否会成为创伤护理的一项进步。这里描述的是在美国一家 civilian创伤中心建立通用供血者O型SWB的过程。

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引用本文的文献

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