Dong Hui Jin, Qian Yuan, Zhang You, Zhao Lin Qing, Zhu Ru Nan, Nong Yi, Mo Zhao Jun, Li Rong Cheng
Laboratory of Virology, Beijing Key Laboratory of Etiology of Viral Diseases in Children, Capital Institute of Pediatrics, Beijing, 100020, China.
Centers for Disease Control and Prevention of Guangxi Province, Nanning, 530028, Guangxi, China.
Arch Virol. 2016 Jul;161(7):1987-92. doi: 10.1007/s00705-016-2852-5. Epub 2016 Apr 21.
Routine surveillance revealed that the prevalence of P[4] rotaviruses circulating in children with acute diarrhea in Guangxi Province, China, increased in 2014. However, VP7 genotyping for these P[4] rotaviruses was unsuccessful. Exhaustive database searching and sequence analysis indicated that the G genotype of these P[4] rotaviruses was G2, and the VP7 genes clustered with recently emerging G2 strains in several countries within an emergent evolutionary lineage that was distinct from the previously designated lineages I-IV as well as lineage V including porcine rotaviruses. Further studies are essential to monitor the potential global spread of this emerging G2 rotavirus.
常规监测显示，2014年中国广西壮族自治区急性腹泻患儿中流行的P[4]型轮状病毒感染率有所上升。然而，对这些P[4]型轮状病毒进行VP7基因分型未获成功。通过详尽的数据库检索和序列分析表明，这些P[4]型轮状病毒的G基因型为G2，其VP7基因与近期在多个国家出现的G2毒株聚集在一个新出现的进化谱系中，该谱系不同于先前指定的I - IV谱系以及包括猪轮状病毒在内的V谱系。进一步的研究对于监测这种新出现的G2型轮状病毒在全球的潜在传播至关重要。
