Brailo V, Firić M, Vučićević Boras V, Andabak Rogulj A, Krstevski I, Alajbeg I
Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Oral Dis. 2016 Sep;22(6):512-6. doi: 10.1111/odi.12493. Epub 2016 May 17.
In spite of extensive research, no effective treatment of primary burning mouth syndrome (BMS) still exists. The aim of this study was to determine the impact of informative intervention/reassurance on pain perception and quality of life in patients with primary BMS.
Informative intervention/reassurance was undertaken in 28 patients diagnosed with primary BMS. Patients received information about all aspects of BMS verbally and in an informative leaflet. Numerical scale (0-10), Pain Catastrophizing Scale and Oral Health Impact Profile-14 (OHIP-14) were used to assess pain intensity, pain perception, and quality of life before the intervention and 6 months after. No other treatment was given to the patients.
Significant reduction in symptom intensity, pain catastrophizing along with positive increase in the quality of life compared with baseline, was observed on a follow-up examination 6 months after the informative intervention (P < 0.001).
The results of this study confirm that objective informing/reassurance of patients with primary BMS can result in decreased catastrophizing and improvement in the quality of life. By eliminating/changing negative patterns of behavior, a reduction in symptoms comparable with pharmacological treatment can be achieved.
尽管进行了广泛研究，但原发性灼口综合征（BMS）仍无有效治疗方法。本研究旨在确定信息干预/安慰对原发性BMS患者疼痛感知和生活质量的影响。
对28例诊断为原发性BMS的患者进行信息干预/安慰。患者通过口头和信息传单了解BMS的各个方面。采用数字评分量表（0-10）、疼痛灾难化量表和口腔健康影响程度量表-14（OHIP-14）在干预前和干预6个月后评估疼痛强度、疼痛感知和生活质量。患者未接受其他治疗。
在信息干预6个月后的随访检查中，观察到与基线相比，症状强度、疼痛灾难化显著降低，生活质量呈积极改善（P < 0.001）。
本研究结果证实，对原发性BMS患者进行客观的信息告知/安慰可减少灾难化并改善生活质量。通过消除/改变负面行为模式，可实现与药物治疗相当的症状减轻。
