Dipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche Unità di Medicina Orale, Patologia Orale e Odontoiatria Geriatrica, Università di Milano, Milan, Italy.
Pain Pract. 2013 Nov;13(8):627-32. doi: 10.1111/papr.12031. Epub 2013 Jan 21.
Burning mouth syndrome (BMS) is a chronic condition most common in middle-aged and elderly women, with prevalence rates in the general population ranging from 0.5% to 5%. Defined by the International Headache Society as "an intraoral burning sensation for which no medical or dental cause can be found," BMS is considered a form of neuropathic pain. The management of BMS remains unsatisfactory. In this pilot study, we investigated the use of acupuncture in a small group of BMS patients. The study group, after 4 refusals, was composed of 10 BMS patients (9 females and 1 male; mean age, 65.2 years; range, from 48 to 80 years; mean duration of BMS, 2.6 years; SD ± 0.8 years). Oral pain/burning sensation (primary outcome) was measured using a visual analogue scale (VAS). Health-related quality of life (secondary outcome) was measured using the 36-item Short-Form Health Survey (SF-36). Acupuncture treatment lasted 8 weeks and consisted of 20 sessions. Patients reported a mean reduction in pain of 0.99 points on the VAS (max 2.1-min 0.1), which, although slight, was statistically significant (Wilcoxon test P < 0.009). No significant improvement in the overall score for quality of life was observed, although subjects receiving acupuncture treatment seemed better able cope with their oral symptoms.
灼口综合征（BMS）是一种常见于中年和老年女性的慢性疾病，普通人群中的患病率在 0.5%至 5%之间。国际头痛协会将其定义为“口腔内烧灼感，找不到医学或牙科原因”，BMS 被认为是一种神经性疼痛。BMS 的治疗仍然不尽如人意。在这项初步研究中，我们调查了小部分 BMS 患者使用针灸的情况。研究组最初有 10 名 BMS 患者（9 名女性和 1 名男性；平均年龄 65.2 岁；年龄范围为 48 至 80 岁；BMS 的平均持续时间为 2.6 年；标准差 ± 0.8 年），经过 4 次拒绝后，最终入组。口腔疼痛/烧灼感（主要结局）采用视觉模拟量表（VAS）进行测量。健康相关生活质量（次要结局）采用 36 项简短健康调查（SF-36）进行测量。针灸治疗持续 8 周，共 20 次。患者报告 VAS 疼痛评分平均降低 0.99 分（最大 2.1 分，最小 0.1 分），虽然幅度较小，但具有统计学意义（Wilcoxon 检验 P < 0.009）。尽管接受针灸治疗的患者似乎能够更好地应对口腔症状，但他们的生活质量总体评分并未显著改善。
