Vayá A, Mira Y, Miralles F, Aznar J
Sangre (Barc). 1989 Feb;34(1):47-9.
Free erythrocyte protoporphirin (FEP), along with diverse haematologic and iron metabolism data, were determined in 60 carriers of the thalassaemic trait (29 beta and 31 delta beta). FEP rates were significantly higher in thalassaemia carriers (39.04 +/- 14.12 micrograms/dl) than in a control group (24.95 +/- 4.70 micrograms/dl) (p less than 0.05). No correlation between FEP and any other iron metabolism parameter, or the severity of anaemia, was found. No FEP differences appeared between the beta (41.06 +/- 16.5 micrograms/dl) and delta beta (37.1 +/- 11.06 micrograms/dl) traits, so, although FEP rates are increased in thalassaemia carriers, they are useless in differentiating between the commonest thalassaemic forms in our country.
对60名地中海贫血特征携带者（29名β型和31名δβ型）测定了游离红细胞原卟啉（FEP）以及各种血液学和铁代谢数据。地中海贫血携带者的FEP水平（39.04±14.12微克/分升）显著高于对照组（24.95±4.70微克/分升）（p<0.05）。未发现FEP与任何其他铁代谢参数或贫血严重程度之间存在相关性。β型（41.06±16.5微克/分升）和δβ型（37.1±11.06微克/分升）特征之间未出现FEP差异，因此，尽管地中海贫血携带者的FEP水平升高，但它们无助于区分我国最常见的地中海贫血类型。
