Vayá A, Mira Y, Martínez M, Miralles F, Aguado C, Aznar J
Sangre (Barc). 1989 Feb;34(1):50-2.
Red-cell deformability was assessed with the Hanss' haemorheometer in 63 carriers of the thalassaemic trait (20 beta and 43 delta beta). Impaired deformability (rigidity index 10.5 +/- 1.4) was present in 80% of the carriers of both beta- and delta beta-traits, as compared with a control group (rigidity index 8.7 +/- 0.6). No correlation was found between such indices and several parameters capable of influencing upon red-cell deformability, namely, MCV, MCH, RDW and MDA. The possibility of any impairment of lipid compounds in red cell membrane is suggested as a cause of decreased deformability in thalassaemia carriers.
使用汉斯血液流变仪对63名地中海贫血特征携带者（20名β型和43名δβ型）的红细胞变形性进行了评估。与对照组（刚性指数8.7±0.6）相比，80%的β型和δβ型特征携带者存在变形性受损（刚性指数10.5±1.4）。未发现这些指标与几个能够影响红细胞变形性的参数之间存在相关性，这些参数即平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）、红细胞分布宽度（RDW）和丙二醛（MDA）。提示红细胞膜中脂质化合物的任何损伤可能是地中海贫血携带者变形性降低的原因。
