Department of Internal Medicine, Saint Peter's University Hospital, New Brunswick, NJ 08901, USA.
World J Gastroenterol. 2009 Dec 7;15(45):5641-6. doi: 10.3748/wjg.15.5641.
Acute pancreatitis (AP) is a rare event in pregnancy, occurring in approximately 3 in 10,000 pregnancies. The spectrum of AP in pregnancy ranges from mild pancreatitis to serious pancreatitis associated with necrosis, abscesses, pseudocysts and multiple organ dysfunction syndromes. Pregnancy related hematological and biochemical alterations influence the interpretation of diagnostic tests and assessment of severity of AP. As in any other disease associated with pregnancy, AP is associated with greater concerns as it deals with two lives rather than just one as in the non-pregnant population. The recent advances in clinical gastroenterology have improved the early diagnosis and effective management of biliary pancreatitis. Diagnostic studies such as endoscopic ultrasound, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography and therapeutic modalities that include endoscopic sphincterotomy, biliary stenting, common bile duct stone extraction and laparoscopic cholecystectomy are major milestones in gastroenterology. When properly managed AP in pregnancy does not carry a dismal prognosis as in the past.
妊娠期胰腺炎（AP）是一种罕见的疾病，约每 10000 例妊娠中发生 3 例。妊娠期 AP 的范围从轻度胰腺炎到严重胰腺炎，伴有坏死、脓肿、假性囊肿和多器官功能障碍综合征。妊娠相关的血液学和生化改变会影响诊断试验的解读和 AP 严重程度的评估。与任何与妊娠相关的疾病一样，AP 引起的关注更大，因为它涉及到两条生命，而不仅仅是像非妊娠人群那样一条生命。临床胃肠病学的最新进展改善了胆源性胰腺炎的早期诊断和有效管理。内镜超声、磁共振胰胆管成像和逆行胰胆管造影等诊断研究以及内镜下括约肌切开术、胆管支架置入术、胆总管结石取出术和腹腔镜胆囊切除术等治疗方式是胃肠病学的重要里程碑。如果得到适当的管理，妊娠期 AP 的预后并不像过去那样悲观。
