Rauscher H, Popp W, Vollmann A, Ritschka L, Zwick H
Lungenabteilung, Krankenhaus der Stadt Wien-Lainz.
Wien Klin Wochenschr. 1989 Mar 17;101(6):200-3.
Obstructive sleep apnea is frequently found in middle-aged men. Usually, these patients are obese and therefore predisposed to hypertension. This study aimed to elucidate the relationships between hypertension, obesity and obstructive sleep apnea in 48 men suffering from sleep apnea. Hypertension was found in 39 of them (= 81%), 27 patients (= 56%) were morbidly obese (Broca index above 125%), 17 patients (= 36%) were moderately obese (Broca index between 100 and 125%) and 4 patients (= 8%) showed normal weight (Broca index below 100%). Severity of sleep apnea did not correlate with obesity or hypertension. Patients with sleep apnea who were hypertensive were significantly (p less than 0.025) more obese than those with normal blood pressure. Compared with an unselected population showing a similar degree of obesity, patients with obstructive sleep apnea showed a higher prevalence of hypertension and this is independent of age. These findings establish sleep apnea as a risk factor for hypertension.
阻塞性睡眠呼吸暂停在中年男性中很常见。通常，这些患者肥胖，因此易患高血压。本研究旨在阐明48名患有睡眠呼吸暂停的男性中高血压、肥胖与阻塞性睡眠呼吸暂停之间的关系。其中39人（=81%）患有高血压，27名患者（=56%）为病态肥胖（布罗卡指数高于125%），17名患者（=36%）为中度肥胖（布罗卡指数在100%至125%之间），4名患者（=8%）体重正常（布罗卡指数低于100%）。睡眠呼吸暂停的严重程度与肥胖或高血压无关。患有高血压的睡眠呼吸暂停患者比血压正常的患者明显更肥胖（p小于0.025）。与未经过挑选但肥胖程度相似的人群相比，阻塞性睡眠呼吸暂停患者的高血压患病率更高，且这与年龄无关。这些发现证实睡眠呼吸暂停是高血压的一个危险因素。
