Guizard Anne-Valerie, Dejardin Olivier, Launay Ludivine, Bara Simona, Lapôtre-Ledoux Bénédicte, Babin Emmanuel, Launoy Guy, Ligier Karine
Registre général des tumeurs du Calvados, Centre F Baclesse, 14000, Caen, France.
U1086 Inserm, Université Caen Basse Normandie, "Cancer et prévention", Centre F Baclesse, 14000, Caen, France.
Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3951-3958. doi: 10.1007/s00405-016-4056-8. Epub 2016 Apr 27.
Head and neck cancers (HNC) have a poor prognosis and a long treatment delay may have a negative impact on this. Some studies have investigated the determinants of this delay but not in the general population and rarely taking into account socio-economic factors. A high-resolution population-based study about cancer management was conducted, using registries in the north-west of France, on HNC diagnosed between 2008 and 2010. The median time between diagnosis and multidisciplinary team meeting (DMI) (N = 1631) was 14 days (Q1: 7 to Q3: 26). The median time between diagnosis and first treatment (DTI) (N = 1519) was 35 days (Q1: 21 to Q3: 54). When the first treatment was radiotherapy, the interval was 54.5 days (Q1: 40 to Q3: 71). In multivariate analysis, DTI was associated with the type of first treatment and place of treatment. For advanced stage HNC, DTI was associated with comorbidities, topography of the cancer and socio-economic status, underprivileged patients being treated later than privileged ones. Given the French governmental cancer plans which set out to coordinate care pathways via nursing coordinators and to improve the availability of radiotherapy, the waiting times observed in this study still seem long. The optimal care pathway should include adapted social management but the DTI was still longer for underprivileged patients.
头颈癌(HNC)的预后较差,治疗延迟时间过长可能会对此产生负面影响。一些研究调查了这种延迟的决定因素,但不是针对普通人群,而且很少考虑社会经济因素。利用法国西北部的登记处,对2008年至2010年期间诊断出的头颈癌进行了一项基于人群的高分辨率癌症管理研究。诊断与多学科团队会诊(DMI)之间的中位时间(N = 1631)为14天(第一四分位数:7至第三四分位数:26)。诊断与首次治疗(DTI)之间的中位时间(N = 1519)为35天(第一四分位数:21至第三四分位数:54)。当首次治疗为放射治疗时,间隔时间为54.5天(第一四分位数:40至第三四分位数:71)。在多变量分析中,DTI与首次治疗的类型和治疗地点有关。对于晚期头颈癌,DTI与合并症、癌症部位和社会经济状况有关,贫困患者比富裕患者接受治疗的时间更晚。鉴于法国政府的癌症计划旨在通过护理协调员协调护理途径并提高放射治疗的可及性,本研究中观察到的等待时间似乎仍然很长。最佳护理途径应包括适当的社会管理,但贫困患者的DTI仍然更长。