Ligier K, Plouvier S, Danzon A, Martin P, Benoît E, Molinié F, Launoy G, Buisset E, Leroy X, Chevalier D, Chaud P, Chérié-Challine L
Registre général des cancers de Lille et de sa région, centre de référence régional en cancérologie, 235, avenue de la Recherche, CS 50086, 59373 Loos cedex, France.
Rev Epidemiol Sante Publique. 2012 Apr;60(2):131-9. doi: 10.1016/j.respe.2011.10.006. Epub 2012 Mar 14.
In 2005, following the first cancer plan of the national health authorities, a general cancer registry was established in northern France, in a territory designated as a "zone in proximity to the city of Lille" (ZPL). The aim of the present work was to evaluate the completeness of the registry's first year of incident cancer registration (2005) and to compare the observed cancer incidence in the "ZPL" with the estimated incidence in France.
Completeness was assessed using the average number of sources per case, the percentage of histological verification and a method of independent case ascertainment (mortality/incidence ratio). A direct standardization on the world population was used to calculate the ZPL/France ratios of standardized incidence rates. Analyses were conducted for 21 cancer sites.
In 2005, 3635 cases of invasive cancer were recorded by the registry. The average number of sources per case was 2.7 and histological proof was available for 91.4% of cases. Mortality/incidence ratios showed satisfactory completeness of the data for men for most cancer sites. For women however, for cancer sites for which the number of cases was low, data will have to be confirmed during the subsequent years of observation. A lack of completeness was found for cutaneous melanoma. In men, an overincidence was identified for cancers of lip-mouth-pharynx, larynx, esophagus, lung, liver, bladder, kidney and colon-rectum. In women, an overincidence has been identified for cancers of lip-mouth-pharynx, liver, bladder, colon-rectum, corpus uteri and ovaries.
The first year of incidence validated at the "Registre général des cancers de Lille et de sa région" shows a completeness of records with regards to studied criteria. The comparison with national data shows an overincidence of cancers related to tobacco and alcohol consumption in the geographical area covered by the registry. The incidence of lip-mouth-pharynx cancer in men is the highest of all French registries.
2005年，在国家卫生当局的首个癌症计划之后，法国北部在一个被指定为“靠近里尔市地区”（ZPL）的区域建立了一个综合癌症登记处。本研究的目的是评估该登记处第一年（2005年）新发癌症登记的完整性，并将“ZPL”地区观察到的癌症发病率与法国的估计发病率进行比较。
使用每个病例的平均信息来源数量、组织学验证百分比和独立病例确定方法（死亡率/发病率比）来评估完整性。采用世界人口直接标准化方法计算标准化发病率的ZPL/法国比率。对21个癌症部位进行了分析。
2005年，登记处记录了3635例浸润性癌症病例。每个病例的平均信息来源数量为2.7，91.4%的病例有组织学证据。死亡率/发病率比显示，大多数癌症部位男性的数据完整性令人满意。然而，对于女性而言，对于病例数较少的癌症部位，数据必须在随后的观察年份中得到确认。皮肤黑色素瘤存在数据不完整的情况。在男性中，唇-口-咽、喉、食管、肺、肝、膀胱、肾和结肠-直肠癌的发病率过高。在女性中，唇-口-咽、肝、膀胱、结肠-直肠、子宫体和卵巢癌的发病率过高。
“里尔及其地区癌症综合登记处”验证的第一年发病率显示，在所研究的标准方面记录具有完整性。与国家数据的比较显示，在登记处覆盖的地理区域中，与烟草和酒精消费相关的癌症发病率过高。男性唇-口-咽癌的发病率在所有法国登记处中最高。
