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大麻素呕吐综合征与躁狂发作的起始

Cannabinoid hyperemesis syndrome and the onset of a manic episode.

作者信息

Gregoire Phillip, Tau Michael, Robertson David

机构信息

University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.

出版信息

BMJ Case Rep. 2016 Apr 27;2016:bcr2016215129. doi: 10.1136/bcr-2016-215129.

Abstract

Cannabinoid hyperemesis syndrome is a rare, recently described, clinically diagnosed condition that is characterised by a chronic history of cannabis use, cyclic nausea and vomiting, symptomatic relief with hot water bathing, and resolution with cessation of use. We present a case of this syndrome concurrent in a patient with bipolar mania. We suggest that a 3-week period of vomiting in the context of this syndrome contributed to the precipitation of a manic episode by lowering mood stabiliser serum levels, and that this syndrome will have significant consequences for the patient's mental health.

摘要

大麻素呕吐综合征是一种罕见的、最近才被描述的临床诊断疾病,其特征为有长期使用大麻史、周期性恶心和呕吐、热水浴可缓解症状以及停用大麻后症状消失。我们报告了一例该综合征与双相躁狂症并发的病例。我们认为,在此综合征背景下持续3周的呕吐通过降低心境稳定剂的血清水平促成了躁狂发作,并且该综合征将对患者的心理健康产生重大影响。

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