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孤立肾患者日间输尿管镜检查及激光碎石术(URSL)的安全性和可行性

Safety and feasibility of day case ureteroscopy and laser lithotripsy (URSL) in patients with a solitary kidney.

作者信息

Ghosh Anngona, Somani Bhaskar K

机构信息

University Hospital Southampton NHS Trust, Southampton, United Kingdom.

出版信息

Cent European J Urol. 2016;69(1):91-5. doi: 10.5173/ceju.2016.709. Epub 2016 Jan 11.

Abstract

INTRODUCTION

The management of nephrolithiasis in patients with a solitary kidney poses a treatment challenge. The study aimed to evaluate the outcomes of ureteroscopy and laser stone fragmentation (URSL) for renal stones in these patients treated in our university teaching hospital.

MATERIAL AND METHODS

Between July 2012 and December 2014, seventeen cases of URSL for stones in a solitary kidney were reviewed. Patient demographics, stone dimensions, perioperative and post-operative outcomes were recorded in a prospectively maintained database. Serum creatinine levels pre-procedure and at follow-up were also compared.

RESULTS

Seventeen cases of URSL were conducted with a mean age of 52.9 ±19.9 years. 8 of the 17 (47%) patients had stones in multiple locations and 13 (76%) were in the lower pole. The mean ± SD stone size and BMI were 13.0 ±8.9 mm and 31.6 ±5.8 kg/m(2), respectively. The stone free rate (SFR) was 82.5%. Fourteen (82.5%) patients were discharged the same day and 16 cases (94%) were discharged within 24 hours. For patients with deranged pre-operative serum creatinine, the mean serum creatinine level improved from 131.2 ±68.3 µmol/L pre-URSL to 106.5 ±36.7 µmol/L at follow-up. There was one Clavien grade II complication with a patient requiring additional antibiotics for post-operative urinary tract infection. There were no other major or minor complications.

CONCLUSIONS

Day case ureteroscopy for stone disease in a solitary kidney is safe and feasible with a low complication rate and an overall improvement in renal function.

摘要

引言

对单肾患者的肾结石进行管理是一项治疗挑战。本研究旨在评估在我们大学教学医院接受治疗的这些患者中,输尿管镜检查和激光碎石术(URSL)治疗肾结石的效果。

材料与方法

回顾了2012年7月至2014年12月期间17例单肾结石患者接受URSL治疗的病例。患者人口统计学资料、结石大小、围手术期和术后结果记录在一个前瞻性维护的数据库中。还比较了术前和随访时的血清肌酐水平。

结果

进行了17例URSL,平均年龄为52.9±19.9岁。17例患者中有8例(47%)结石位于多个部位,13例(76%)位于下极。结石平均大小±标准差和BMI分别为13.0±8.9mm和31.6±5.8kg/m²。结石清除率(SFR)为82.5%。14例(82.5%)患者在当天出院,16例(94%)在24小时内出院。对于术前血清肌酐异常的患者,平均血清肌酐水平从URSL术前的131.2±68.3µmol/L改善至随访时的106.5±36.7µmol/L。有1例Clavien II级并发症,1例患者因术后尿路感染需要额外使用抗生素。无其他严重或轻微并发症。

结论

单肾结石疾病的日间输尿管镜检查安全可行,并发症发生率低,肾功能总体改善。

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