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2
Exploring mechanisms of protein influence on calcium oxalate kidney stone formation.探讨蛋白质影响草酸钙肾结石形成的机制。
Urolithiasis. 2021 Aug;49(4):281-290. doi: 10.1007/s00240-021-01247-5. Epub 2021 Feb 15.
3
Guideline of guidelines for kidney and bladder stones.肾结石和膀胱结石指南的指南
Turk J Urol. 2020 Nov;46(Supp. 1):S104-S112. doi: 10.5152/tud.2020.20315. Epub 2020 Oct 9.
4
Identifying unwarranted variation in clinical practice between healthcare providers in England: Analysis of administrative data over time for the Getting It Right First Time programme.识别英格兰医疗保健提供者之间临床实践中的不必要差异:针对“一次做对”计划的随时间变化的行政数据的分析。
J Eval Clin Pract. 2021 Aug;27(4):743-750. doi: 10.1111/jep.13477. Epub 2020 Sep 30.
5
Patients treated for uric acid stones reoccur more often and within a shorter interval compared to patients treated for calcium stones.与接受钙结石治疗的患者相比,接受尿酸结石治疗的患者复发更频繁,且复发间隔更短。
Can Urol Assoc J. 2020 Nov;14(11):E555-E559. doi: 10.5489/cuaj.6259.
6
The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: the percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole kidney stones randomised controlled trial (PUrE RCT) protocol.经皮肾镜碎石术、软性输尿管镜碎石术和体外冲击波碎石术治疗肾下极结石的临床和成本效益:肾下极结石随机对照试验(PUrE RCT)方案。
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Evaluation of the economic burden of kidney stone disease in the UK: a retrospective cohort study with a mean follow-up of 19 years.评估英国肾结石病的经济负担:一项平均随访时间为 19 年的回顾性队列研究。
BJU Int. 2020 Apr;125(4):586-594. doi: 10.1111/bju.14991. Epub 2020 Jan 24.
8
Obesity and kidney stone disease: a systematic review.肥胖与肾结石疾病:一项系统综述。
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9
Effect of Stone Composition on the Outcomes of Semi-Rigid Ureteroscopy Using Holmium: Yttrium-Aluminum-Garnet Laser or Pneumatic Lithotripsy.结石成分对使用钬:钇铝石榴石激光或气压弹道碎石术的半硬性输尿管镜检查结果的影响。
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输尿管镜取石术的治疗结果会因结石成分而异吗?一项前瞻性分析。

Do outcomes of ureteroscopic stone treatment vary with stone composition? A prospective analysis.

作者信息

Johnston Maximilian J, Sinha Mriganka, Pietropaolo Amelia, Somani Bhaskar K

机构信息

Department of Urology, University Hospital of Southampton, Southampton, United Kingdom.

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

出版信息

Cent European J Urol. 2022;75(4):405-408. doi: 10.5173/ceju.2022.185. Epub 2022 Nov 5.

DOI:10.5173/ceju.2022.185
PMID:36794032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9903168/
Abstract

INTRODUCTION

Urinary tract calculi are commonly treated with ureteroscopy and laser stone fragmentation (URSL). The composition of calculi depends on underlying patient factors. Stones associated with metabolic or infectious conditions are sometimes thought to be more difficult to treat. This analysis explores whether the composition of calculi impacts on stone-free and complication rates.

MATERIAL AND METHODS

A prospectively maintained database of patients undergoing URSL between 2012-2021 was used to explore records for patients with uric acid (Group A), infection (Group B) and calcium oxalate monohydrate (Group C) calculi. Patients who had undergone URSL to treat ureteric or renal calculi were included. Patient demographics, stone parameters and operative details were collected, with the principal outcomes being stone-free rate (SFR) and associated complications.

RESULTS

A total of 352 patients were included (58 Group A, 71 Group B and 223 Group C patients) and had their data analysed. SFR was >90% for all three groups and a single Clavien-Dindo grade III complication was noted. No significant differences were found between the groups for complications, SFR and day case rates.

CONCLUSIONS

This cohort of patients demonstrated that outcomes were similar for three different types of urinary tract calculi, which form for differing reasons. URSL appears to be an effective, safe treatment for all stone types with comparable results.

摘要

引言

尿路结石通常采用输尿管镜检查和激光碎石术(URSL)进行治疗。结石的成分取决于患者的潜在因素。与代谢或感染性疾病相关的结石有时被认为更难治疗。本分析探讨结石成分是否会影响结石清除率和并发症发生率。

材料与方法

使用一个前瞻性维护的2012年至2021年间接受URSL治疗患者的数据库,以探究尿酸结石患者(A组)、感染性结石患者(B组)和一水草酸钙结石患者(C组)的记录。纳入接受URSL治疗输尿管或肾结石的患者。收集患者的人口统计学数据、结石参数和手术细节,主要结局为结石清除率(SFR)和相关并发症。

结果

共纳入352例患者(A组58例、B组71例、C组223例)并对其数据进行分析。三组的结石清除率均>90%,且记录到1例Clavien-Dindo III级并发症。三组在并发症、结石清除率和日间手术率方面未发现显著差异。

结论

该队列患者表明,三种不同类型的尿路结石(形成原因不同)的治疗结果相似。URSL似乎是一种对所有结石类型均有效且安全的治疗方法,结果相当。