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单纯采用刮宫术或联合其他治疗方法处理的外源性剖宫产瘢痕妊娠:33例病例系列及并发症分析

Exogenous cesarean scar pregnancies managed by suction curettage alone or in combination with other therapeutic procedures: A series of 33 cases and analysis of complication profile.

作者信息

Özdamar Özkan, Doğer Emek, Arlıer Sefa, Çakıroğlu Yiğit, Ergin Rahime Nida, Köpük Şule Yıldırım, Çalışkan Eray

机构信息

Department of Obstetrics and Gynecology, Istanbul Medeniyet University, Faculty of Medicine, Istanbul, Turkey.

Department of Obstetrics and Gynecology, School of Medicine, Kocaeli University, Kocaeli, Turkey.

出版信息

J Obstet Gynaecol Res. 2016 Aug;42(8):927-35. doi: 10.1111/jog.13017. Epub 2016 Apr 28.

Abstract

AIM

The aim of this study was to review our exogenous cesarean scar pregnancy (CSP) cases that were managed through transabdominal ultrasound (TAUS)-guided suction curettage either alone or with a concomitant additional therapeutic modality. The study was carried out over a 6-year period and we compared clinical outcomes, success rates and complication profiles between the two therapeutic approaches.

METHODS

A total of 33 exogenous CSP patients who were managed by suction curettage were extracted from the medical records. The patients were analyzed according to the intervention applied in the two groups as: TAUS-guided suction curettage alone (Group 1); and additional therapeutic tools, such as systemic or intracavitary administration of methotrexate and intracavitary ethanol instillation, in combination with suction curettage (Group 2). Basic demographic and clinical characteristics of women experiencing hemorrhagic complications and those who did not after the treatment were also compared.

RESULTS

There were no cases of uterine perforation, hysterectomy or unresponsiveness to treatment in our analyzed CSP cases. Four patients, two in each group, required blood transfusion. Our success rate in the overall patient population was 87.8% (29/33). Fourteen out of 16 patients who were treated with TAUS-guided suction curettage alone, and 15 out of 17 patients who received other interventional treatment modalities preceding suction curettage revealed successful resolution of the CSP without any complication (P = 0.948). Clinical and demographic characteristics of women who experienced any hemorrhagic complication did not significantly differ from those who did not.

CONCLUSION

In appropriate CSP cases, TAUS-guided suction curettage appears to be a reliable treatment option with acceptable success rates and similar complication profile to other therapeutic options.

摘要

目的

本研究旨在回顾我们通过经腹超声(TAUS)引导下刮宫术单独治疗或联合其他治疗方式处理的外源性剖宫产瘢痕妊娠(CSP)病例。该研究历时6年,我们比较了两种治疗方法的临床结局、成功率及并发症情况。

方法

从病历中提取33例接受刮宫术治疗的外源性CSP患者。根据两组所采用的干预措施将患者分为:单纯TAUS引导下刮宫术组(第1组);以及联合刮宫术采用其他治疗手段,如全身或腔内给予甲氨蝶呤及腔内注入乙醇组(第2组)。还比较了治疗后出现出血并发症患者与未出现出血并发症患者的基本人口统计学和临床特征。

结果

在我们分析的CSP病例中,未出现子宫穿孔、子宫切除或治疗无效的情况。4例患者需要输血,每组各2例。我们在总体患者人群中的成功率为87.8%(29/33)。单纯接受TAUS引导下刮宫术治疗的16例患者中有14例,在刮宫术前接受其他介入治疗方式的17例患者中有15例,CSP均成功解决且无任何并发症(P = 0.948)。出现出血并发症的女性与未出现出血并发症的女性在临床和人口统计学特征上无显著差异。

结论

在合适的CSP病例中,TAUS引导下刮宫术似乎是一种可靠的治疗选择,成功率可接受,且并发症情况与其他治疗选择相似。

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