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剖宫产瘢痕妊娠病例中以吸刮术作为一线治疗:早期妊娠的可行性与有效性

Suction curettage as first line treatment in cases with cesarean scar pregnancy: feasibility and effectiveness in early pregnancy.

作者信息

Polat Ibrahim, Ekiz Ali, Acar Deniz Kanber, Kaya Basak, Ozkose Burak, Ozdemir Cagdas, Talay Hasan, Gedikbasi Ali

机构信息

a Department of Obstetrics and Gynecology , Maternal-Fetal Medicine Unit, Kanuni Sultan Suleyman Training and Research Hospital , Istanbul , Turkey and.

b Department of Obstetrics and Gynecology , Mardin Maternity and Children Disease Hospital , Mardin , Turkey.

出版信息

J Matern Fetal Neonatal Med. 2016;29(7):1066-71. doi: 10.3109/14767058.2015.1034100. Epub 2015 Apr 21.

Abstract

OBJECTIVE

A cesarean scar pregnancy (CSP) is an extremely rare form of an ectopic pregnancy, which is defined as the localization of a fertilized ovum surrounded by uterine muscular fiber and scar tissue. The objective of this study was to discuss the management options for CSPs in a singleton center. In the current study, we discussed the current management options for CSPs based on our 6 years of experience.

MATERIAL AND METHODS

A retrospective evaluation of diagnosed and treated 26 patients with CSPs in Istanbul Kanuni Sultan Suleyman Training and Research Hospital during a 6-year period was discussed. Suction curettage was performed as first-line treatment in patients with a gestation <8 weeks and myometrial thickness >2 mm.

RESULTS

Twenty-two (84.6%) patients with CSPs were initially treated surgically (curettage and hysterotomy) and four (15.4%) patients were treated medically with methotrexate injections. Vacuum aspiration was performed in 19 patients as a first-line treatment, six of them needed an additional Foley balloon catheter to be inserted for tamponade because of persistent vaginal bleeding. Suction curettage was successful in 12 patients. The treatment rate for suction curettage with or without Foley balloon catheter tamponade was 16 of 19 (84.2%).

CONCLUSION

The early diagnosis of a CSP (7-8 weeks gestation) with a β-hCG level <17.000 mIU/ml and a myometrial thickness >2 mm can be treated with suction curettage with or without placement of a uterine Foley balloon as curative treatment.

摘要

目的

剖宫产瘢痕妊娠(CSP)是一种极为罕见的异位妊娠形式,定义为受精卵着床于子宫肌纤维和瘢痕组织内。本研究的目的是探讨单中心CSP的管理方案。在本研究中,我们基于6年的经验讨论了CSP的当前管理方案。

材料与方法

对伊斯坦布尔卡努尼·苏丹·苏莱曼培训与研究医院6年间诊断并治疗的26例CSP患者进行回顾性评估。对于孕周<8周且肌层厚度>2 mm的患者,刮宫术作为一线治疗方法。

结果

22例(84.6%)CSP患者最初接受手术治疗(刮宫术和子宫切开术),4例(15.4%)患者接受甲氨蝶呤注射药物治疗。19例患者作为一线治疗进行了真空吸引术,其中6例因持续阴道出血需要额外插入Foley球囊导管进行填塞。刮宫术在12例患者中成功。无论有无Foley球囊导管填塞,刮宫术的治疗成功率为19例中的16例(84.2%)。

结论

对于妊娠7 - 8周、β - hCG水平<17,000 mIU/ml且肌层厚度>2 mm的CSP,早期诊断可采用刮宫术,无论是否放置子宫Foley球囊作为根治性治疗。

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