el-Naggar M A, Schaberg F J, Phillips M R
Department of Anesthesiology, Memorial Hospital of Rhode Island, Pawtucket 02860.
Arch Surg. 1989 May;124(5):568-70. doi: 10.1001/archsurg.1989.01410050058011.
Fifty patients undergoing cholecystectomy either electively or urgently were treated in the postoperative period with the intrapleural injection of 30 mL of 0.75% bupivacaine hydrochloride with epinephrine (1:200,000). The frequency of narcotic administration and the postoperative stay were compared with those of 50 historical controls. The group receiving intrapleural regional analgesia had significant, prolonged pain relief requiring minimal narcotic analgesics in the first 24 hours postoperatively and had a significantly shortened hospital stay. There were no complications related to catheter insertion or bupivacaine toxic effects. This technique is safe and effective in controlling perioperative pain.
五十例择期或急诊行胆囊切除术的患者在术后接受了胸膜腔内注射30毫升含肾上腺素（1:200,000）的0.75%盐酸布比卡因治疗。将其麻醉剂使用频率和术后住院时间与50例历史对照患者进行了比较。接受胸膜腔内区域镇痛的患者术后24小时内疼痛缓解显著且持续时间长，所需麻醉性镇痛药极少，住院时间也显著缩短。未出现与导管插入或布比卡因毒性作用相关的并发症。该技术在控制围手术期疼痛方面安全有效。
