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支架置入输尿管内尿液流动的流体结构分析

Fluid Structural Analysis of Urine Flow in a Stented Ureter.

作者信息

Gómez-Blanco J Carlos, Martínez-Reina F Javier, Cruz Domingo, Pagador J Blas, Sánchez-Margallo Francisco M, Soria Federico

机构信息

Jesús Usón Minimally Invasive Surgery Centre, Carretera N-521, km 41.8, 10071 Cáceres, Spain.

Department of Mechanical Engineering, Universidad de Sevilla, C∖Camino Descubrimientos, S/N, Isla de la Cartuja, 41092 Sevilla, Spain.

出版信息

Comput Math Methods Med. 2016;2016:5710798. doi: 10.1155/2016/5710798. Epub 2016 Mar 31.

Abstract

Many urologists are currently studying new designs of ureteral stents to improve the quality of their operations and the subsequent recovery of the patient. In order to help during this design process, many computational models have been developed to simulate the behaviour of different biological tissues and provide a realistic computational environment to evaluate the stents. However, due to the high complexity of the involved tissues, they usually introduce simplifications to make these models less computationally demanding. In this study, the interaction between urine flow and a double-J stented ureter with a simplified geometry has been analysed. The Fluid-Structure Interaction (FSI) of urine and the ureteral wall was studied using three models for the solid domain: Mooney-Rivlin, Yeoh, and Ogden. The ureter was assumed to be quasi-incompressible and isotropic. Data obtained in previous studies from ex vivo and in vivo mechanical characterization of different ureters were used to fit the mentioned models. The results show that the interaction between the stented ureter and urine is negligible. Therefore, we can conclude that this type of models does not need to include the FSI and could be solved quite accurately assuming that the ureter is a rigid body and, thus, using the more simple Computational Fluid Dynamics (CFD) approach.

摘要

目前,许多泌尿科医生正在研究输尿管支架的新设计,以提高手术质量和患者术后恢复情况。为了在设计过程中提供帮助,已经开发了许多计算模型来模拟不同生物组织的行为,并提供一个逼真的计算环境来评估支架。然而,由于所涉及组织的高度复杂性,他们通常会进行简化,以使这些模型的计算要求降低。在本研究中,分析了具有简化几何形状的双J形输尿管支架与尿液流动之间的相互作用。使用固体域的三种模型研究了尿液与输尿管壁之间的流固耦合(FSI):Mooney-Rivlin模型、Yeoh模型和Ogden模型。假定输尿管为准不可压缩且各向同性的。利用先前研究中从不同输尿管的体外和体内力学特性获得的数据来拟合上述模型。结果表明,带支架输尿管与尿液之间的相互作用可以忽略不计。因此,我们可以得出结论,这类模型不需要考虑流固耦合,并且在假定输尿管为刚体的情况下,可以使用更简单的计算流体动力学(CFD)方法相当准确地求解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c18/4830759/a85cb030c3e9/CMMM2016-5710798.001.jpg

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