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两性霉素B脂质体治疗小鼠组织胞浆菌病

Liposomal amphotericin B therapy of murine histoplasmosis.

作者信息

Graybill J R, Bocanegra R

机构信息

Department of Medicine, University of Texas Health Science Center at San Antonio, USA.

出版信息

Antimicrob Agents Chemother. 1995 Aug;39(8):1885-7. doi: 10.1128/AAC.39.8.1885.

Abstract

Liposomal amphotericin B (AmBisome) was compared with amphotericin B deoxycholate for the treatment of disseminated murine histoplasmosis. Liposomal amphotericin B was well tolerated and, milligram for milligram, was as potent as amphotericin B deoxycholate.

摘要

将两性霉素B脂质体(安必素)与两性霉素B脱氧胆酸盐用于治疗播散性小鼠组织胞浆菌病,并进行了比较。两性霉素B脂质体耐受性良好,且每毫克的效力与两性霉素B脱氧胆酸盐相当。

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