居家服用多种药物的老年人的用药依从性：现有研究的系统评价
MEDICATION ADHERENCE IN ELDERLY WITH POLYPHARMACY LIVING AT HOME: A SYSTEMATIC REVIEW OF EXISTING STUDIES.
作者信息
Zelko Erika, Klemenc-Ketis Zalika, Tusek-Bunc Ksenija
机构信息
Department of Family Medicine, Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Department of Family Medicine, Faculty of Medicine, University of Maribor, Maribor, Slovenia; Department of Family Medicine, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
出版信息
Mater Sociomed. 2016 Apr;28(2):129-32. doi: 10.5455/msm.2016.28.129-132. Epub 2016 Mar 25.
BACKGROUND
We wanted to systematically review the available evidence to evaluate the drug adherence in elderly with polypharmacy living at home.
METHODS
We performed a literature search using MEDLINE, ISI Web of Science, ProQuest, EMBASE, SCOPUS, Springer Link, Sage Journals and CINAHL. We used the following terms: Medication Adherence, Medication Compliance, Polypharmacy, and Elderly. The search was limited to English-language articles. We included only clinical trials, systematic reviews, meta-analysis and cross-sectional studies.
RESULTS
A total of seven articles were included in this systematic review after applying the search strategy. Six studies dealt with the prevalence of medication adherence and its correlates in patients aged 65 years or more with polypharmacy. Two studies dealt with the effect of various interventions on medication adherence in patients aged 65 years or more with polypharmacy.
CONCLUSION
The available literature on the polypharmacy and drug adherence in elderly living at home is scarce and further studies are needed.
背景
我们希望系统地回顾现有证据，以评估居家的老年多重用药患者的药物依从性。
方法
我们使用MEDLINE、ISI 科学网、ProQuest、EMBASE、SCOPUS、Springer Link、Sage期刊和CINAHL进行文献检索。我们使用了以下术语：药物依从性、药物顺应性、多重用药和老年人。检索仅限于英文文章。我们仅纳入临床试验、系统评价、荟萃分析和横断面研究。
结果
应用检索策略后，本系统评价共纳入7篇文章。6项研究探讨了65岁及以上多重用药患者的药物依从性患病率及其相关因素。2项研究探讨了各种干预措施对65岁及以上多重用药患者药物依从性的影响。
结论
关于居家老年人多重用药和药物依从性的现有文献较少，需要进一步研究。
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