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男性下尿路症状患者早期有效管理膀胱过度活动症的障碍。

Barriers to early and effective overactive bladder management in male patients with lower urinary tract symptoms.

作者信息

Rasner Paul, Arcila-Ruiz Maria, Silva José Ailton Fernandes, Nuanthaisong Umaphorn, Cho Sung Yung, Chung Eric

机构信息

Urological Department, Moscow State University of Medicine and Dentistry, Moscow, Russia.

Department of Urology, Hospital Universitario San Ignacio, Bogota, Colombia.

出版信息

PLoS One. 2025 Jul 23;20(7):e0328723. doi: 10.1371/journal.pone.0328723. eCollection 2025.

Abstract

Overactive bladder is underdiagnosed and undertreated in men as symptoms overlap with benign prostatic obstruction. This study identified barriers urologists encountered in effectively managing overactive bladder in men with lower urinary tract symptoms. 60 urologists recruited across Australia, Brazil, Colombia, Russia, South Korea and Thailand via convenience sampling participated in in-depth interviews. They were asked about their understanding and management of overactive bladder in men with lower urinary tract symptoms. Thematic analysis identified six themes: (1) overactive bladder diagnosis in men with lower urinary tract symptoms is complicated by the multi-factorial causes of storage symptoms; (2) patient-reported outcome tools are underutilized by urologists; (3) stigmatization and normalization of overactive bladder discourage men from seeking care; (4) challenges exist in tracking overactive bladder symptoms and in patient-urologist communication; (5) the underestimation of overactive bladder contributes to the non-urgency of its management; and (6) urologists may not fully appreciate the trade-offs between different overactive bladder treatments. Encouraging patient-reported outcome tool usage and differentiating the safety profiles of antimuscarinics and beta-3 agonists may facilitate timelier overactive bladder diagnosis and increase confidence in adding-on treatment.

摘要

由于症状与良性前列腺梗阻重叠,男性膀胱过度活动症的诊断不足且治疗不充分。本研究确定了泌尿科医生在有效管理下尿路症状男性的膀胱过度活动症时遇到的障碍。通过便利抽样在澳大利亚、巴西、哥伦比亚、俄罗斯、韩国和泰国招募的60名泌尿科医生参与了深入访谈。他们被问及对下尿路症状男性膀胱过度活动症的理解和管理。主题分析确定了六个主题:(1)下尿路症状男性膀胱过度活动症的诊断因储尿症状的多因素病因而复杂化;(2)泌尿科医生未充分利用患者报告的结局工具;(3)膀胱过度活动症的污名化和正常化阻碍男性寻求治疗;(4)跟踪膀胱过度活动症症状以及患者与泌尿科医生沟通方面存在挑战;(5)对膀胱过度活动症的低估导致其治疗缺乏紧迫性;(6)泌尿科医生可能没有充分认识到不同膀胱过度活动症治疗方法之间的权衡。鼓励使用患者报告的结局工具并区分抗毒蕈碱药物和β-3激动剂的安全性概况可能有助于更及时地诊断膀胱过度活动症并增加对附加治疗的信心。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ca0/12286356/97927406b973/pone.0328723.g001.jpg

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