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评估使用手动药盒和服药提醒应用程序来提高马哈拉施特拉邦农村老年人口用药依从性的可接受性和可行性。

Evaluation of acceptability and feasibility of using manual pill organizers and pill reminder apps for improving medication adherence among elderly population from rural Maharashtra.

作者信息

Nimkar Radhika K, Balkhande Rajesh W, Patil Rakesh S, Agarwal Dhiraj M, Apte Aditi A

机构信息

KEM Hospital Research Centre, Vadu Rural Health Program, Pune, Maharashtra, India.

出版信息

Indian J Pharmacol. 2025 May 1;57(3):150-158. doi: 10.4103/ijp.ijp_960_24. Epub 2025 Jul 9.

Abstract

BACKGROUND

Approximately 40%-75% of elderly individuals suffering from chronic diseases are nonadherent to medications. Manual pill organizers (MPO) and pill reminder apps (PRAs) are simple interventions that can improve medication adherence. This was a mixed-methods study to understand the feasibility and acceptability of MPO and a locally developed PRA amongst elderly individuals from rural Maharashtra.

MATERIALS AND METHODS

Sixty elderly individuals aged 60-80 years taking three or more oral medications with access to a smartphone were randomized to receive MPO, PRA, or MPO + PRA for 3 months (n = 30). The outcome measures included acceptability and feasibility using qualitative methods, and usability was measured using a system usability scale.

RESULTS

Both MPO and PRA demonstrated good system usability and ease of independent use. The findings of the qualitative study highlighted reduced dependency on caregivers, reduced chance of missing a pill, and ease of carrying medicines during travel as benefits of MPO. User-friendliness, ability to take medication on time, and caregivers' satisfaction were reported benefits with PRA. Reported challenges included initial hesitancy, the additional workload of filling the MPO, alarm malfunctions, and dependency on family members for using PRA. Medication nonadherence due to forgetfulness significantly improved from 52% to 65% at baseline to 90%-100% at the end as reported using Medication Adherence Rating System-5. Participants in the combined group did not report any difficulty using the two interventions together.

CONCLUSION

The study demonstrates good feasibility and acceptability of MPOs and indigenously developed PRA either alone or in combination among the Indian rural elderly population. CTRI registration: CTRI/2024/01/061975 (Registered on- January 29, 2024).

摘要

背景

约40%-75%患有慢性病的老年人不遵医嘱服药。手动药盒(MPO)和服药提醒应用程序(PRA)是可提高服药依从性的简单干预措施。这是一项混合方法研究,旨在了解MPO和一款在马哈拉施特拉邦农村地区自主开发的PRA在老年人群中的可行性和可接受性。

材料与方法

60名年龄在60-80岁、服用三种或更多口服药物且能使用智能手机的老年人被随机分为三组,分别接受MPO、PRA或MPO+PRA,为期3个月(n=30)。结果指标包括使用定性方法评估的可接受性和可行性,以及使用系统可用性量表测量的易用性。

结果

MPO和PRA均显示出良好的系统易用性和独立使用的便利性。定性研究结果强调,MPO的好处包括减少对护理人员的依赖、减少漏服药物的几率以及旅行时便于携带药品。PRA的好处包括用户友好性、按时服药的能力以及护理人员的满意度。报告的挑战包括最初的犹豫、填充MPO的额外工作量、闹钟故障以及使用PRA对家庭成员的依赖。根据药物依从性评分系统-5报告,因遗忘导致的用药不依从从基线时的52%显著改善至研究结束时的90%-100%。联合组的参与者未报告同时使用这两种干预措施有任何困难。

结论

该研究表明,MPO和自主开发的PRA单独或联合使用在印度农村老年人群中具有良好的可行性和可接受性。临床试验注册:CTRI/2024/01/061975(于2024年1月29日注册)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3c0/12348747/dcd2ec373422/IJPharm-57-150-g001.jpg

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