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菌丝的向化性在真菌致病性中的作用。

Hyphal chemotropism in fungal pathogenicity.

机构信息

Departamento de Genética, Campus de Excelencia Internacional Agroalimentario ceiA3, Universidad de Córdoba, 14071 Córdoba, Spain.

Departamento de Genética, Campus de Excelencia Internacional Agroalimentario ceiA3, Universidad de Córdoba, 14071 Córdoba, Spain.

出版信息

Semin Cell Dev Biol. 2016 Sep;57:69-75. doi: 10.1016/j.semcdb.2016.04.020. Epub 2016 May 2.

DOI:10.1016/j.semcdb.2016.04.020
PMID:27150623
Abstract

The ability to grow as filamentous hyphae defines the lifestyle of fungi. Hyphae are exposed to a variety of chemical stimuli such as nutrients or signal molecules from mating partners and host organisms. How fungi sense and process this chemical information to steer hyphal growth is poorly understood. Saccharomyces cerevisiae and Neurospora crassa have served as genetic models for the identification of cellular components functioning in chemotropism. A recent study in the pathogen Fusarium oxysporum revealed distinct MAPK pathways governing hyphal growth towards nutrient sources and sex pheromones or plant signals, suggesting an unanticipated complexity of chemosensing during fungus-host interactions.

摘要

能够以丝状菌丝生长定义真菌的生活方式。菌丝暴露于各种化学刺激物,例如营养物质或来自交配伴侣和宿主生物体的信号分子。真菌如何感知和处理这些化学信息以引导菌丝生长还知之甚少。酿酒酵母和粗糙脉孢菌已被用作遗传模型,以鉴定在趋化性中起作用的细胞成分。最近在病原体尖孢镰刀菌中的一项研究揭示了不同的 MAPK 途径,这些途径控制着菌丝向营养源和性信息素或植物信号生长,这表明在真菌与宿主相互作用过程中化学感应具有出乎意料的复杂性。

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