Thakarar Kinna, Asiimwe Stephen B, Cheng Debbie M, Forman Leah, Ngabirano Christine, Muyindike Winnie R, Emenyonu Nneka I, Samet Jeffrey H, Hahn Judith A
Center for Outcomes Research and Evaluation, Maine Medical Center, Portland, ME, USA.
Department of Medicine, Mbarara Regional Referral Hospital, Mbarara, Uganda.
AIDS Behav. 2016 Oct;20(10):2408-2417. doi: 10.1007/s10461-016-1421-y.
The brewing of alcohol in Ugandan households is common, yet little is known about its relationship with alcohol consumption in HIV-infected individuals. We performed a cross-sectional analysis to assess the association between household brewing and unhealthy alcohol consumption among 387 HIV-infected adults in a prospective study examining the association between alcohol consumption and HIV-disease progression. Household brewing was defined as participants reporting that they or a household member home-brewed alcohol. Logistic regression was used to assess the association between household brewing and unhealthy alcohol consumption, defined as phosphatidylethanol (PEth) level ≥50 ng/ml or AUDIT-C (modified to measure the prior 3 months) positive. Sixty-six (17.0 %) participants reported household brewing. Household brewers had higher odds of unhealthy alcohol consumption (AOR 2.27, 95 % CI 1.26-4.12). Among HIV-infected individuals, household brewing was associated with unhealthy alcohol consumption. Interventions to reduce alcohol consumption in this population could target household brewers.
在乌干达家庭中，自酿酒精很常见，但人们对其与艾滋病毒感染者饮酒之间的关系知之甚少。在一项前瞻性研究中，我们进行了横断面分析，以评估387名艾滋病毒感染成年人中家庭自酿酒精与不健康饮酒之间的关联，该研究旨在探讨饮酒与艾滋病毒疾病进展之间的关系。家庭自酿酒精被定义为参与者报告他们自己或家庭成员在家自酿酒精。采用逻辑回归分析来评估家庭自酿酒精与不健康饮酒之间的关联，不健康饮酒被定义为磷脂酰乙醇（PEth）水平≥50 ng/ml或酒精使用障碍识别测试简表（AUDIT-C，修改后用于测量前3个月情况）呈阳性。66名（17.0%）参与者报告有家庭自酿酒精的情况。家庭自酿酒精者出现不健康饮酒的几率更高（调整后的比值比为2.27，95%置信区间为1.26 - 4.12）。在艾滋病毒感染者中，家庭自酿酒精与不健康饮酒有关。针对该人群减少饮酒的干预措施可以针对家庭自酿酒精者。
