Wang Yuanzheng, Li Guangsen, Sun Yanhong, Shan Guoxin, Xu Rui, Guo Lijuan
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Department of Ultrasound, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Ultrasound Med Biol. 2016 Aug;42(8):1741-9. doi: 10.1016/j.ultrasmedbio.2016.03.023. Epub 2016 May 5.
This study assessed whether 2-D speckle tracking echocardiography (STE) derived from left ventricular (LV) strain and rotation is capable of detecting LV dysfunction associated with alcoholic cardiomyopathy. Ninety-two male chronic alcoholic patients were grouped by alcohol intake amount and duration: mild (n = 30; >90 mg ethanol daily, 3-5 d per wk for 5-8 y); moderate (n = 30; >90-150 mg ethanol daily, 3-5 d per wk for 9-20 y); and severe (n = 32; >150 mg ethanol daily, 6-7 d per wk for >10 y). Thirty non-drinkers were recruited as healthy controls. Rotation and twist values were lower in the severe group compared with the other groups (p < 0.05). The moderate and severe alcohol groups demonstrated lower longitudinal, circumferential and radial strain values and early to late filling (E/A) ratios compared with the mild group and non-drinkers (all p < 0.05). 2-D STE-derived strain and rotation are reliable echocardiographic markers for detecting left ventricular dysfunction in patients at risk of developing alcoholic cardiomyopathy.
本研究评估了源自左心室（LV）应变和旋转的二维斑点追踪超声心动图（STE）是否能够检测与酒精性心肌病相关的左心室功能障碍。92名男性慢性酒精中毒患者按酒精摄入量和饮酒时间分组：轻度组（n = 30；每日乙醇摄入量>90 mg，每周3 - 5天，持续5 - 8年）；中度组（n = 30；每日乙醇摄入量>90 - 150 mg，每周3 - 5天，持续9 - 20年）；重度组（n = 32；每日乙醇摄入量>150 mg，每周6 - 7天，持续>10年）。招募30名不饮酒者作为健康对照。与其他组相比，重度组的旋转和扭转值较低（p < 0.05）。与轻度组和不饮酒者相比，中度和重度酒精组的纵向、圆周和径向应变值以及早期至晚期充盈（E/A）比值较低（所有p < 0.05）。源自二维STE的应变和旋转是检测有患酒精性心肌病风险患者左心室功能障碍的可靠超声心动图标志物。
