El-Hadad Samia, Sachs Maike Katja, Barrense-Dias Yara, Granell Joan Carles Suris, Niggli Angela, Leeners Brigitte
Department of Reproductional Endocrinology, Zurich University Hospital, Zurich, Switzerland
Department of Reproductional Endocrinology, Zurich University Hospital, Zurich, Switzerland.
BMJ Open. 2025 Feb 12;15(2):e089681. doi: 10.1136/bmjopen-2024-089681.
This study aimed to evaluate the human papillomavirus (HPV) vaccination status among a representative sample of young adults (YAs) with a special focus on the catch-up vaccination uptake among the male population in Switzerland.
Data were extracted from an online self-administered questionnaire survey, conducted as a representative cross-sectional study in 2017. To understand correlations between vaccination uptake and sociodemographic characteristics, sexual health, and sexual behaviour, we performed bivariate analysis and multivariate regression analysis.
Out of a total of 7142 participants, 2155 female and 996 male cisgender participants remained for statistical evaluation after excluding homosexual/bisexual study participants, those with gender dysphoria or those without knowledge of their vaccination status.
The primary outcome of this study was to investigate HPV vaccination rates among female and male YAs in Switzerland. As secondary outcomes, we assessed uptake of catch-up vaccination and identified key factors influencing HPV vaccination uptake.
Vaccination rates were significantly higher in the female group (40.9%), while not wanting to be vaccinated and doubting benefits and necessity of the vaccine were main reasons for non-vaccination. Vaccination coverage among male YAs was very low (7.8%), primarily due to insufficient information. Parents not being Swiss-born, a higher family socioeconomic status and having had a gynaecological visit at a younger age correlated with HPV vaccination uptake for female YAs. In the male group, participants with a higher number of lifetime partners and a younger age at first steady partnership were more likely to report a positive vaccination status. Knowledge about the benefits of catch-up vaccination was very limited among both genders.
The lack of knowledge about benefits of HPV vaccination contributes to low vaccine uptake, especially occurring among the male population, must be addressed. Given the number of people who reported not knowing whether they were vaccinated or not, it is crucial to ensure that there is a thorough discussion about HPV and the protection the vaccine provides when presenting for vaccination.
本研究旨在评估年轻成年人（YA）代表性样本中的人乳头瘤病毒（HPV）疫苗接种状况，特别关注瑞士男性人群中的补种疫苗接种情况。
数据来自2017年进行的一项具有代表性的横断面在线自填式问卷调查。为了解疫苗接种率与社会人口学特征、性健康和性行为之间的相关性，我们进行了双变量分析和多变量回归分析。
在总共7142名参与者中，排除同性恋/双性恋研究参与者、有性别焦虑症者或不知道自己疫苗接种状况者后，剩余2155名女性和996名男性顺性别参与者进行统计评估。
本研究的主要结果是调查瑞士年轻男性和女性的HPV疫苗接种率。作为次要结果，我们评估了补种疫苗的接种情况，并确定了影响HPV疫苗接种的关键因素。
女性组的疫苗接种率显著更高（40.9%），而不想接种疫苗以及对疫苗的益处和必要性存疑是未接种疫苗的主要原因。年轻男性的疫苗接种覆盖率非常低（7.8%），主要是由于信息不足。父母非瑞士出生、家庭社会经济地位较高以及年轻时进行过妇科检查与年轻女性的HPV疫苗接种有关。在男性组中，终身伴侣数量较多且首次稳定恋爱关系时年龄较小的参与者更有可能报告接种状况为阳性。两性对补种疫苗益处的了解都非常有限。
必须解决对HPV疫苗益处缺乏了解导致疫苗接种率低的问题，尤其是在男性人群中。鉴于有相当数量的人表示不知道自己是否接种过疫苗，在进行疫苗接种时，确保对HPV及其提供的保护进行全面讨论至关重要。
