Drubach Laura A
Department of Radiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.
PET Clin. 2012 Jul;7(3):293-301. doi: 10.1016/j.cpet.2012.04.004. Epub 2012 Jun 26.
Skeletal imaging of children with fluorine-18 ((18)F) NaF harnesses the superior imaging characteristics of positron emission tomography (PET) and the improved biodistribution of the fluoride tracer compared with standard nuclear techniques, resulting in excellent quality images. Bone malignancy in children is less common than in adults, and the evaluation of benign skeletal disorders represents a larger fraction of indications in the pediatric versus adult population. (18)F NaF PET imaging has been successfully applied to various benign disorders, particularly trauma and sports medicine applications.
利用氟-18(¹⁸F)氟化钠对儿童进行骨骼成像,结合了正电子发射断层扫描(PET)卓越的成像特性以及与标准核技术相比更优的氟化物示踪剂生物分布,从而生成高质量图像。儿童骨恶性肿瘤比成人少见,在儿科人群中,对良性骨骼疾病的评估在检查指征中所占比例高于成人。¹⁸F氟化钠PET成像已成功应用于各种良性疾病,尤其是创伤和运动医学领域。