Abikhzer Gad, Kennedy John, Israel Ora
Department of Nuclear Medicine, Rambam Health Care Campus, 6 Ha'Aliya Street, Haifa 31096, Israel.
Department of Nuclear Medicine, Rambam Health Care Campus, 6 Ha'Aliya Street, Haifa 31096, Israel; B. and R. Rapaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
PET Clin. 2012 Jul;7(3):315-28. doi: 10.1016/j.cpet.2012.04.005. Epub 2012 Jun 26.
Conventional planar and SPECT bone scintigraphy has long been used and familiarity with this tracer and imaging technique is excellent. (18)F NaF PET/CT represents an alternative tracer and imaging modality for the assessment of the skeleton, with the potential to become the gold standard in functional bone imaging. This article compares the pharmacokinetics, protocols, clinical performance, and cost-effectiveness of the 2 modalities. Technological advances and future directions of both modalities are also discussed.
传统的平面骨闪烁显像和单光子发射计算机断层扫描（SPECT）骨闪烁显像长期以来一直被使用，并且对这种示踪剂和成像技术非常熟悉。氟（18）化钠正电子发射断层显像/计算机断层扫描（PET/CT）是用于评估骨骼的另一种示踪剂和成像方式，有可能成为功能骨成像的金标准。本文比较了这两种方式的药代动力学、方案、临床性能和成本效益。还讨论了这两种方式的技术进展和未来方向。
