Struttura Complessa Dipartimento Universitario Geriatria e Malattie Metaboliche dell'Osso, Città della Salute e della Scienza-Molinette, Torino, Italy.
Struttura Complessa Geriatria e Cure Intermedie, Azienda Sanitaria Ospedaliera Santa Croce e Carle, Cuneo, Italy.
J Am Geriatr Soc. 2016 May;64(5):1114-9. doi: 10.1111/jgs.14103. Epub 2016 May 10.
To determine whether emergency department (ED) length of stay before ward admission is associated with incident delirium in older adults.
Prospective cohort study.
Hospital.
Individuals aged 75 and older without delirium at ED entry, coma, aphasia, stroke, language barrier, psychiatric disorder, or alcohol abuse (N = 330).
On ED admission, individuals underwent standardized evaluation of comorbidity (Cumulative Illness Rating Scale), cognitive impairment (Short Portable Mental Status Questionnaire), functional independence (activities of daily living, instrumental activities of daily living), pain (Numeric Rating Scale), and acute clinical conditions (Acute Physiology and Chronic Health Evaluation II). During the first 3 days after ward admission, the presence of delirium (defined as ≥1 delirium episodes within 72 hours) was assessed daily using a rapid assessment for delirium (4AT scale). ED length of stay was calculated as the time (hours) between ED registration and when the person left the ED.
ED length of stay longer than 10 hours (odds ratio (OR) = 2.23, 95% confidence interval (CI) = 1.13-4.41), moderate to severe cognitive impairment (OR = 5.47, 95% CI = 2.76-10.85), and older age (OR = 1.07, 95% CI = 1.01-1.13) were associated with delirium onset.
ED length of stay longer than 10 hours was associated with greater risk of delirium in hospitalized older adults, after adjusting for age and cognitive impairment.
确定急诊(ED)入院前的住院时间是否与老年人的事件性谵妄有关。
前瞻性队列研究。
医院。
无 ED 入院时谵妄、昏迷、失语、中风、语言障碍、精神障碍或酒精滥用的 75 岁及以上个体(N=330)。
ED 入院时,对个体进行共病(累积疾病评分量表)、认知障碍(简易精神状态问卷)、功能独立性(日常生活活动、工具性日常生活活动)、疼痛(数字评分量表)和急性临床状况(急性生理学和慢性健康评估 II)的标准化评估。在病房入院后的头 3 天内,每天使用快速谵妄评估(4AT 量表)评估谵妄的发生情况(定义为 72 小时内出现≥1 次谵妄发作)。ED 住院时间的计算方法是从 ED 登记到患者离开 ED 的时间(小时)。
ED 住院时间超过 10 小时(优势比(OR)=2.23,95%置信区间(CI)=1.13-4.41)、中重度认知障碍(OR=5.47,95% CI=2.76-10.85)和年龄较大(OR=1.07,95% CI=1.01-1.13)与谵妄发作相关。
在调整年龄和认知障碍后,ED 住院时间超过 10 小时与住院老年患者谵妄风险增加相关。