University Heart Center Zurich, Zurich, Switzerland
University Heart Center Zurich, Zurich, Switzerland.
Eur Heart J. 2016 Dec 14;37(47):3495-3502. doi: 10.1093/eurheartj/ehw165. Epub 2016 May 8.
Paravalvular leak (PVL) occurs after both surgical and transcatheter valve replacement/implantation. It can lead to haemolysis, heart failure and may increase the risk of endocarditis. Percutaneous closure has significantly less morbidity than re-operation and is therefore often the therapy of choice. Percutaneous PVL closure can make an important difference for patients and can improve patient prognosis. These procedures can be intricate and larger case series and research is needed to further develop and improve these procedures.
瓣周漏(PVL)发生于外科手术和经导管瓣膜置换/植入之后。它可导致溶血、心力衰竭,并可能增加心内膜炎的风险。经皮封堵术的发病率显著低于再次手术,因此通常是首选治疗方法。经皮 PVL 封堵术可为患者带来显著获益,并改善患者预后。这些操作可能很复杂,需要更大的病例系列和研究来进一步开发和改进这些操作。