Hamilton Nicholas, Hingorany Shipra, Mazar Michael
Medicine, University of California Los Angeles (UCLA) David Geffen School of Medicine, Los Angeles, USA.
Cardiology, University of California Los Angeles (UCLA) David Geffen School of Medicine, Los Angeles, USA.
Cureus. 2025 Jul 16;17(7):e88069. doi: 10.7759/cureus.88069. eCollection 2025 Jul.
Dark-colored urine is often referred to as hematuria; however, this is an assumption that can often be misleading. In the evaluation of dark-colored urine, distinguishing between true hematuria, hemoglobinuria, and myoglobinuria is essential, as each indicates different underlying pathologies and requires targeted diagnostic and management strategies. Visualization of dark-colored urine often leads to an isolated urologic evaluation, and assessment for more infrequent causes of this phenomenon may be obscured. Clinicians tend to anchor on common urologic causes of dark-colored urine or rely on dipstick analysis alone, thus failing to perform a more systemic evaluation. We present a case of persistent hematuria with cardiac origins that remained undiagnosed for many months. A detailed history and attention to hematologic indices should be pursued when urologic causes of hematuria prove to be unrevealing.
深色尿液常被称为血尿;然而,这一假设往往具有误导性。在评估深色尿液时,区分真性血尿、血红蛋白尿和肌红蛋白尿至关重要,因为每种情况都表明不同的潜在病理状况,且需要有针对性的诊断和管理策略。深色尿液的外观往往导致仅进行泌尿系统评估,而对该现象较少见原因的评估可能被忽视。临床医生往往局限于深色尿液常见的泌尿系统病因,或仅依赖试纸分析,从而未能进行更全面的评估。我们报告一例源于心脏的持续性血尿病例,该病例数月未得到诊断。当血尿的泌尿系统病因检查无果时,应详细询问病史并关注血液学指标。