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烧伤面积小于全身表面积15%时早期切除植皮与延迟皮肤移植的比较:一项非随机临床试验

Early Excision and Grafting versus Delayed Skin Grafting in Burns Covering Less than 15% of Total Body Surface Area; A Non- Randomized Clinical Trial.

作者信息

Ayaz Mehdi, Bahadoran Hamid, Arasteh Peyman, Keshavarzi Abdolkhalegh

机构信息

Department of Surgerym, Shiraz Burn Research Center, Ghotboddin Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.

Department of General Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Bull Emerg Trauma. 2014 Oct;2(4):141-5.

Abstract

OBJECTIVE

To compare outcome of patients with burns covering less than 15% of total body surface area(TBSA) undergoing early excision and grafting or delayed skin grafting.

METHOD

This was a non-randomized clinical trial including 54 patients with less than 15% TBSA burn referring to Ghotboddin Hospital of Shiraz. They were assigned to two study groups, each group including 27 patients: the early excision and grafting group (EEG group) and the delayed grafting group (DG group). Patients were followed postoperatively for 6 months. Hospital stay, graft success rate, itching score and scar formation during 6 months of follow-up were recorded and compared between two study groups.

RESULTS

During the study 1 patient was lost to follow-up in early excision and grafting group. Baseline characteristics were comparable between two study groups. The graft success rate was significantly higher in those patients who underwent early excision and grafting when compared to delayed grafting group (96.88% vs. 92.88%; p=0.033). However the length of hospital stay, itching and scar scores were comparable between two study groups after 6 months of follow-up.

CONCLUSION

In patients with burns covering less than 15% TBSA, early excision and grafting is associated with higher graft success rates compared to the delayed excision and grafting. How ever length of hospital stay, itching and scar formation is comparable between the two techniques.

摘要

目的

比较烧伤面积小于总体表面积(TBSA)15%的患者接受早期切除植皮或延迟植皮的效果。

方法

这是一项非随机临床试验,纳入了设拉子Ghotboddin医院收治的54例TBSA烧伤面积小于15%的患者。他们被分为两个研究组,每组27例:早期切除植皮组(EEG组)和延迟植皮组(DG组)。术后对患者进行6个月的随访。记录并比较两个研究组的住院时间、植皮成功率、瘙痒评分和随访6个月期间的瘢痕形成情况。

结果

研究期间,早期切除植皮组有1例患者失访。两个研究组的基线特征具有可比性。与延迟植皮组相比,接受早期切除植皮的患者植皮成功率显著更高(96.88%对92.88%;p=0.033)。然而,随访6个月后,两个研究组的住院时间、瘙痒和瘢痕评分具有可比性。

结论

对于烧伤面积小于TBSA 15%的患者,与延迟切除植皮相比,早期切除植皮的植皮成功率更高。然而,两种技术的住院时间、瘙痒和瘢痕形成情况相当。

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