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LC-MS/MS as a tool for TDM services: Where are we?

作者信息

Shipkova Maria, Svinarov Dobrin

机构信息

Central Institute for Clinical Chemistry and Laboratory Medicine, Klinikum Stuttgart, Kriegsbergstrasse 60, D-70174, Stuttgart, Germany.

Department of Clinical Laboratory and Clinical Pharmacology, Alexander University Hospital, Faculty of Medicine, Medical University of Sofia, St. G. Sofiiski 1 Blvd., 1431 Sofia, Bulgaria.

出版信息

Clin Biochem. 2016 Sep;49(13-14):1009-23. doi: 10.1016/j.clinbiochem.2016.05.001. Epub 2016 May 6.

DOI:10.1016/j.clinbiochem.2016.05.001

PMID:27163969

Abstract

摘要

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LC-MS/MS as a tool for TDM services: Where are we?

Clin Biochem. 2016 Sep;49(13-14):1009-23. doi: 10.1016/j.clinbiochem.2016.05.001. Epub 2016 May 6.

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J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Feb 1;883-884:33-49. doi: 10.1016/j.jchromb.2011.09.041. Epub 2011 Sep 29.

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J Pharm Biomed Anal. 2013 Dec;86:123-6. doi: 10.1016/j.jpba.2013.08.001. Epub 2013 Aug 11.

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Biomed Chromatogr. 2020 Jan;34(1):e4623. doi: 10.1002/bmc.4623. Epub 2019 Nov 27.

Alternative matrices for therapeutic drug monitoring of immunosuppressive agents using LC-MS/MS.

Bioanalysis. 2015;7(8):1037-58. doi: 10.4155/bio.15.35.

Therapeutic drug monitoring by LC-MS-MS with special focus on anti-infective drugs.

Anal Bioanal Chem. 2010 Nov;398(6):2573-94. doi: 10.1007/s00216-010-3986-z. Epub 2010 Jul 22.

Experiences from using LC-MS/MS for analysis of immunosuppressive drugs in a TDM service.

Clin Biochem. 2016 Sep;49(13-14):1024-31. doi: 10.1016/j.clinbiochem.2016.06.013. Epub 2016 Jun 29.

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LC-MS/MS as a tool for TDM services: Where are we?

作者信息

Shipkova Maria, Svinarov Dobrin

机构信息

Central Institute for Clinical Chemistry and Laboratory Medicine, Klinikum Stuttgart, Kriegsbergstrasse 60, D-70174, Stuttgart, Germany.

Department of Clinical Laboratory and Clinical Pharmacology, Alexander University Hospital, Faculty of Medicine, Medical University of Sofia, St. G. Sofiiski 1 Blvd., 1431 Sofia, Bulgaria.

出版信息

Clin Biochem. 2016 Sep;49(13-14):1009-23. doi: 10.1016/j.clinbiochem.2016.05.001. Epub 2016 May 6.

DOI:10.1016/j.clinbiochem.2016.05.001

PMID:27163969

Abstract

摘要

相似文献

LC-MS/MS as a tool for TDM services: Where are we?

Clin Biochem. 2016 Sep;49(13-14):1009-23. doi: 10.1016/j.clinbiochem.2016.05.001. Epub 2016 May 6.

Therapeutic drug monitoring and LC-MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Feb 1;883-884:33-49. doi: 10.1016/j.jchromb.2011.09.041. Epub 2011 Sep 29.

Advances in antifungal drug measurement by liquid chromatography-mass spectrometry.

Clin Chim Acta. 2019 Apr;491:132-145. doi: 10.1016/j.cca.2019.01.023. Epub 2019 Jan 25.

[Some thoughts on the links between LC-MS/MS and therapeutic drug monitoring].

Ann Biol Clin (Paris). 2015 Jan-Feb;73(1):49-53. doi: 10.1684/abc.2014.1008.

Therapeutic Drug Monitoring of the new targeted anticancer agents imatinib, nilotinib, dasatinib, sunitinib, sorafenib and lapatinib by LC tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jul 15;877(22):1982-96. doi: 10.1016/j.jchromb.2009.04.045. Epub 2009 May 13.

Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant.

J Pharm Biomed Anal. 2013 Dec;86:123-6. doi: 10.1016/j.jpba.2013.08.001. Epub 2013 Aug 11.

Bioanalytical LC-MS/MS validation of therapeutic drug monitoring assays in oncology.

Biomed Chromatogr. 2020 Jan;34(1):e4623. doi: 10.1002/bmc.4623. Epub 2019 Nov 27.

Alternative matrices for therapeutic drug monitoring of immunosuppressive agents using LC-MS/MS.

Bioanalysis. 2015;7(8):1037-58. doi: 10.4155/bio.15.35.

Therapeutic drug monitoring by LC-MS-MS with special focus on anti-infective drugs.

Anal Bioanal Chem. 2010 Nov;398(6):2573-94. doi: 10.1007/s00216-010-3986-z. Epub 2010 Jul 22.

Experiences from using LC-MS/MS for analysis of immunosuppressive drugs in a TDM service.

Clin Biochem. 2016 Sep;49(13-14):1024-31. doi: 10.1016/j.clinbiochem.2016.06.013. Epub 2016 Jun 29.

引用本文的文献

A High-Performance Liquid Chromatography-Mass Spectrometry method for simultaneous determination of dolutegravir, nevirapine, efavirenz, rifampicin and rifapentine concentrations in human plasma.

medRxiv. 2025 Jun 9:2025.06.08.25329229. doi: 10.1101/2025.06.08.25329229.

A Laboratory Protocol for Routine Therapeutic Drug Monitoring of Beta-Lactams Antimicrobials in Horses and Dogs.

Antibiotics (Basel). 2025 Apr 9;14(4):390. doi: 10.3390/antibiotics14040390.

Exploring the Most Effective Strategy for Purine Metabolite Quantification in Veterinary Medicine Using LC-MS/MS.

Vet Sci. 2025 Mar 3;12(3):230. doi: 10.3390/vetsci12030230.

Impact of clinical preparation steps and use of sex-specific reference for accurate antibiotic monitoring in body fluids.

Commun Med (Lond). 2025 Apr 16;5(1):120. doi: 10.1038/s43856-025-00823-9.

Implantable photoelectrochemical-therapeutic methotrexate monitoring system with dual-atomic docking strategy.

Nat Commun. 2025 Feb 18;16(1):1747. doi: 10.1038/s41467-025-57084-2.

Development of Simultaneous Drug Concentration Measurement Method Using an Automated Pretreatment Liquid Chromatography/Tandem Mass Spectrometry System for Therapeutic Drug Monitoring.

Pharmaceutics. 2024 Aug 28;16(9):1138. doi: 10.3390/pharmaceutics16091138.

Hyphenation of microflow chromatography with electrospray ionization mass spectrometry for bioanalytical applications focusing on low molecular weight compounds: A tutorial review.

Mass Spectrom Rev. 2025 May-Jun;44(3):491-512. doi: 10.1002/mas.21898. Epub 2024 Jul 1.

Pharmacological Treatments and Therapeutic Drug Monitoring in Patients with Chronic Pain.

Pharmaceutics. 2023 Aug 5;15(8):2088. doi: 10.3390/pharmaceutics15082088.

High throughput LC/ESI-MS/MS method for simultaneous analysis of 20 oral molecular-targeted anticancer drugs and the active metabolite of sunitinib in human plasma.

Heliyon. 2023 Jun 2;9(6):e16926. doi: 10.1016/j.heliyon.2023.e16926. eCollection 2023 Jun.

Recommendations for the measurement of sexual steroids. A step forward in the silent revolution of mass spectrometry.

Adv Lab Med. 2023 Mar 10;4(1):1-4. doi: 10.1515/almed-2023-0022. eCollection 2023 Apr.

LC-MS/MS as a tool for TDM services: Where are we?

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LC-MS/MS as a tool for TDM services: Where are we?

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