Czosnyka Zofia, Czosnyka Marek, Pickard John D, Chari Aswin
Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
Acta Neurochir Suppl. 2016;122:347-51. doi: 10.1007/978-3-319-22533-3_68.
Shunt testing independent of manufacturers provides knowledge that can significantly improve the management of patients with hydrocephalus. The Cambridge Shunt Evaluation Laboratory was created 20 years ago. Thanks to financial support from the Department of Health (1993-1998), all shunts in use in the UK were systematically evaluated, with "blue reports" being published. Later new devices were tested as they appeared in public domain.Twenty-six models have been evaluated. The majority of the valves had a non-physiologically low hydrodynamic resistance that may result in over-drainage, both related to posture and during nocturnal cerebral vasogenic waves. A long distal catheter increases the resistance of these valves by 100-200 %. Drainage through valves without a siphon-preventing mechanism is very sensitive to body posture. Shunts with siphon-preventing accessories offer a reasonable resistance to negative outlet pressure. Bench parameters were used to test shunt performance in vivo using infusion tests. A criterion for correctly performing a shunt procedure was established. Pressure measured in the shunt prechamber during the plateau phase of infusion should not remain more than 5 mmHg above the le shunt's operating pressure plus hydrodynamic resistance of the valve multiplied by the infusion rate. "Critical levels" for every shunt and every performance level have been used in the shunt testing wizard of ICM+ software.
独立于制造商进行分流器测试能够提供可显著改善脑积水患者管理的知识。剑桥分流器评估实验室于20年前成立。得益于卫生部(1993 - 1998年)的资金支持,英国所有在用的分流器都得到了系统评估,并发布了“蓝色报告”。后来新出现的设备也在其进入公共领域时进行了测试。已评估了26种型号。大多数阀门的流体动力阻力在生理上处于较低水平,这可能导致过度引流,无论是与体位有关还是在夜间脑血管源性波动期间。较长的远端导管会使这些阀门的阻力增加100% - 200%。没有防虹吸机制的阀门的引流对身体姿势非常敏感。带有防虹吸附件的分流器对负出口压力具有合理的阻力。使用灌注测试,利用实验台参数在体内测试分流器性能。确立了正确进行分流手术的标准。在灌注平台期,分流器前腔测量的压力不应比分流器的工作压力加上阀门的流体动力阻力乘以灌注速率高出5 mmHg以上。ICM +软件的分流器测试向导中使用了每种分流器和每个性能水平的“临界水平”。