Department of Neurosurgery, Cambridge University Hospital National Health Service Trust, Cambridge, United Kingdom.
J Neurosurg. 2014 Mar;120(3):697-707. doi: 10.3171/2013.11.JNS121895. Epub 2014 Jan 3.
The Cambridge Shunt Evaluation Laboratory was established 20 years ago. This paper summarizes the findings of that laboratory for the clinician.
Twenty-six models of valves have been tested long-term in the shunt laboratory according to the expanded International Organization for Standardization 7197 standard protocol.
The majority of the valves had a nonphysiologically low hydrodynamic resistance (from 1.5 to 3 mm Hg/[ml/min]), which may result in overdrainage related to posture and during nocturnal cerebral vasogenic waves. A long distal catheter increases the resistance of these valves by 100%-200%. Drainage through valves without a siphon-preventing mechanism is very sensitive to body posture, which may result in grossly negative intracranial pressure. Siphon-preventing accessories offer a reasonable resistance to negative outlet pressure; however, accessories with membrane devices may be blocked by raised subcutaneous pressure. In adjustable valves, the settings may be changed by external magnetic fields of intensity above 40 mT (exceptions: ProGAV, Polaris, and Certas). Most of the magnetically adjustable valves produce large distortions on MRI studies.
The behavior of a valve revealed during testing is of relevance to the surgeon and may not be adequately described in the manufacturer's product information. The results of shunt testing are helpful in many circumstances, such as the initial choice of shunt and the evaluation of the shunt when its dysfunction is suspected.
剑桥分流管评估实验室成立于 20 年前。本文总结了该实验室为临床医生提供的发现。
根据国际标准化组织 7197 标准扩展协议,在分流管实验室中对 26 种型号的阀门进行了长期测试。
大多数阀门具有非生理性低液压阻力(1.5 至 3mmHg/[ml/min]),这可能导致与姿势相关的过度引流,以及夜间脑血管源性波期间的过度引流。长的远端导管会使这些阀门的阻力增加 100%-200%。没有防虹吸装置的阀门的排水对体位非常敏感,可能导致颅内压明显为负。防虹吸附件提供了对负出口压力的合理阻力;然而,带有膜装置的附件可能会被升高的皮下压力阻塞。在可调节阀门中,外部磁场强度超过 40mT(例外:ProGAV、Polaris 和 Certas)可能会改变设定值。大多数可调节磁阀门在 MRI 研究中会产生较大的变形。
在测试中揭示的阀门行为与外科医生有关,制造商的产品信息可能无法充分描述。分流管测试的结果在许多情况下都很有帮助,例如最初选择分流管,以及怀疑分流管功能障碍时对其进行评估。