HIV latency reversal research and the potential effects on the central nervous system: is concern warranted?
作者信息
Anderson Albert M, Schinazi Raymond F, Tyor William R
机构信息
Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA;
Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
出版信息
J Int AIDS Soc. 2016 May 9;19(1):21008. doi: 10.7448/IAS.19.1.21008. eCollection 2016.
Abstract
摘要
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本文引用的文献
1
HIV-1 Eradication: Early Trials (and Tribulations).HIV-1根除：早期试验（及磨难）。
Trends Mol Med. 2016 Jan;22(1):10-27. doi: 10.1016/j.molmed.2015.11.004. Epub 2015 Dec 12.
2
HIV-associated neurocognitive disorders: Five new things.与人类免疫缺陷病毒相关的神经认知障碍：五个新情况。
Neurol Clin Pract. 2015 Jun;5(3):224-231. doi: 10.1212/CPJ.0000000000000117.
3
HIV eradication symposium: will the brain be left behind?消除HIV研讨会：大脑会被遗忘吗？
J Neurovirol. 2015 Jun;21(3):322-34. doi: 10.1007/s13365-015-0322-6. Epub 2015 Mar 7.
4
Macaque species susceptibility to simian immunodeficiency virus: increased incidence of SIV central nervous system disease in pigtailed macaques versus rhesus macaques.猕猴物种对猿猴免疫缺陷病毒的易感性：与恒河猴相比，猪尾猕猴感染猿猴免疫缺陷病毒后中枢神经系统疾病的发病率增加。
J Neurovirol. 2015 Apr;21(2):148-58. doi: 10.1007/s13365-015-0313-7. Epub 2015 Feb 12.
5
Latest animal models for anti-HIV drug discovery.用于抗HIV药物研发的最新动物模型。
Expert Opin Drug Discov. 2015 Feb;10(2):111-23. doi: 10.1517/17460441.2015.975201. Epub 2014 Oct 28.
6
Antiretroviral-free HIV-1 remission and viral rebound after allogeneic stem cell transplantation: report of 2 cases.异基因干细胞移植后无抗逆转录病毒治疗的HIV-1缓解及病毒反弹：2例报告
Ann Intern Med. 2014 Sep 2;161(5):319-27. doi: 10.7326/M14-1027.
7
Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.富马酸二甲酯，一种免疫调节剂和抗氧化反应诱导剂，可抑制 HIV 复制和巨噬细胞介导的神经毒性：HIV 神经保护的一种新型候选药物。
J Immunol. 2011 Nov 15;187(10):5015-25. doi: 10.4049/jimmunol.1101868. Epub 2011 Oct 5.
8
Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport.人类免疫缺陷病毒-1 的神经毒性：病毒蛋白和轴突运输。
Neurotox Res. 2012 Jan;21(1):79-89. doi: 10.1007/s12640-011-9279-2. Epub 2011 Sep 27.
9
Simian immunodeficiency virus macaque models of HIV latency.猿猴免疫缺陷病毒猴 HIV 潜伏期模型。
Curr Opin HIV AIDS. 2011 Jan;6(1):57-61. doi: 10.1097/COH.0b013e32834086ce.
10
Eradication of HIV from the brain: reasons for pause.从大脑中根除 HIV：暂停的原因。
AIDS. 2011 Mar 13;25(5):577-80. doi: 10.1097/QAD.0b013e3283437d2f.
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